Overview
Binds to specific receptors on thymocytes and mature T-cells, requiring zinc for biological activity.
Proposed mechanism
Thymulin is a nonapeptide produced by thymic epithelial cells that induces T-cell differentiation and modulates cytokine production in lung tissue.
What the evidence supports
Most data comes from preclinical animal studies. Human clinical trial evidence is limited or absent.
Graded Animal
Evidence drawn from in vivo animal models or in vitro systems. Mechanistically informative; translation to humans is unproven.
Key citations
Representative primary sources, including results that did not favour the compound.
- [1]
Thymulin and immunity
· DOI:10.1016/S0165-2478(99)00157-3 · 1999
- [2]
Thymic peptides review
· DOI:10.1016/j.cyto.2017.07.020 · 2017
- [3]
Thymulin and immunity (1999)
· · 0
- [4]
Thymic peptides review (2017)
· · 0
Citation records in this build are illustrative placeholders for the design.
Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.