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The library

149 compounds. Every one graded.

Filter by research area or by how strong the evidence actually is. Profiles graded Animal or Anecdotal are not hidden they are labelled, which is more useful.

Clinical
15
Human-limited
61
Animal
54
Anecdotal
19

149 of 149 profiles

ACTH 1-39

Clinical

Full-length adrenal hormone with broad receptor activity

ACTH 1-39 is the full-length, biologically active form of adrenocorticotropic hormone, a 39-amino acid peptide naturally secreted by the anterior pituitary gland. It primarily stimulates the adrenal cortex to produce cortisol, aldosterone, and adrenal androgens. Beyond adrenal signaling, ACTH 1-39 exerts direct effects on the brain, immune system, and peripheral tissues via melanocortin receptors.

0 RCT · 0 human · 0 preclinical

Immune

Cagrilintide

Clinical

Once-weekly amylin analogue for weight loss

Cagrilintide is a long-acting acylated amylin analogue developed by Novo Nordisk for the treatment of obesity and type 2 diabetes. It mimics the pancreatic hormone amylin to reduce appetite, slow gastric emptying, and promote satiety. In clinical trials, it has been studied both as a monotherapy and in combination with semaglutide (as CagriSema), demonstrating meaningful and sustained body weight reduction.

0 RCT · 0 human · 0 preclinical

metabolic

Cagrisema (2.5mg + 2.5mg)

Clinical

Dual amylin-GLP-1 therapy for superior weight loss

Cagrisema is a fixed-ratio combination of cagrilintide (a long-acting amylin analogue) and semaglutide (a GLP-1 receptor agonist), each at 2.5 mg per dose. This dual-hormone therapy is designed to provide additive and potentially synergistic effects on appetite suppression, glycemic control, and body weight reduction beyond what either agent achieves alone. It is currently under clinical investigation by Novo Nordisk for the treatment of obesity and type 2 diabetes.

0 RCT · 0 human · 0 preclinical

metabolic

Erythropoietin (EPO)

Clinical

Oxygen-boosting hormone for endurance and anemia

Erythropoietin (EPO) is a glycoprotein hormone naturally produced primarily by the kidneys that regulates red blood cell production. Recombinant human EPO (rHuEPO) mimics this endogenous hormone to stimulate erythropoiesis in the bone marrow, increasing oxygen-carrying capacity. It is clinically approved for anemia associated with chronic kidney disease, chemotherapy, and certain other conditions, but is also widely misused as a performance-enhancing agent in endurance sports.

0 RCT · 0 human · 0 preclinical

Cardiovascular

Gonadorelin Acetate

Clinical

Preserve natural testosterone via HPG axis activation

Gonadorelin Acetate is a synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH), produced and secreted by the hypothalamus. It stimulates the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby supporting endogenous testosterone and estrogen production. It is used clinically to assess pituitary function, treat hypogonadism, support fertility, and is increasingly used alongside anabolic protocols to preserve testicular function.

0 RCT · 0 human · 0 preclinical

sexual

Human Chorionic Gonadotropin (HCG)

Clinical

The LH Mimic for Hormonal Restoration

Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced by the placenta during pregnancy, structurally similar to luteinizing hormone (LH). In clinical and research settings, it is used to stimulate testosterone production in men, support fertility, and maintain testicular function during or after anabolic steroid use. It acts directly on the gonads to mimic LH signaling, making it a cornerstone of hormonal restoration protocols.

0 RCT · 0 human · 0 preclinical

sexual

Human Growth Hormone (HGH)

Clinical

The master anabolic and lipolytic growth hormone

Human Growth Hormone (HGH) is a 191-amino acid peptide hormone naturally secreted by the anterior pituitary gland that regulates growth, body composition, and metabolism. In clinical and performance contexts, recombinant HGH (rhGH) is administered exogenously to mimic or augment endogenous GH signaling. It is one of the most studied anabolic and lipolytic compounds in endocrinology, with established uses in GH deficiency, muscle-wasting conditions, and anti-aging protocols.

0 RCT · 0 human · 0 preclinical

growth

Human Menopausal Gonadotropin (HMG)

Clinical

Dual gonadotropin for fertility and testicular function

Human Menopausal Gonadotropin (HMG) is a purified preparation of gonadotropins extracted from the urine of postmenopausal women, containing both Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) activity in approximately equal ratios. In clinical medicine it is used to stimulate ovulation in women and spermatogenesis in men, particularly those with hypogonadotropic hypogonadism. In performance and fertility contexts, HMG is used alongside or after hCG to restore or maintain testicular function, intratesticular testosterone production, and sperm output.

0 RCT · 0 human · 0 preclinical

sexual

Mazdutide

Clinical

Dual GLP-1/glucagon agonist for metabolic health

Mazdutide is a dual GLP-1/glucagon receptor co-agonist peptide developed by Innovent Biologics, originally derived from oxyntomodulin. It simultaneously activates both GLP-1 and glucagon receptors to produce robust reductions in body weight, blood glucose, and hepatic fat. Clinical trials in China have demonstrated significant efficacy for obesity and type 2 diabetes management.

0 RCT · 0 human · 0 preclinical

metabolic

Melanotan I

Clinical

Clinical-grade melanocyte activator for photoprotection

Melanotan I (afamelanotide) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that potently stimulates melanogenesis, increasing skin pigmentation without requiring UV exposure. It was developed primarily to protect individuals with photosensitive conditions such as erythropoietic protoporphyria (EPP) from painful phototoxic reactions. Beyond tanning, it has demonstrated anti-inflammatory, photoprotective, and potentially immunomodulatory effects in clinical and preclinical studies.

0 RCT · 0 human · 0 preclinical

skin

Oxytocin Acetate

Clinical

The bonding hormone for trust and connection

Oxytocin Acetate is the acetate salt form of oxytocin, a naturally occurring nonapeptide hormone synthesized in the hypothalamus and released by the posterior pituitary gland. It plays central roles in social bonding, trust, stress reduction, sexual function, and uterine contraction. Research has expanded its potential applications to include anxiety reduction, prosocial behavior enhancement, and modulation of the hypothalamic-pituitary-adrenal (HPA) axis.

0 RCT · 0 human · 0 preclinical

mood

PT-141

Clinical

Central nervous system sexual desire activator

PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist originally derived from the tanning peptide Melanotan II. It is used to treat hypoactive sexual desire disorder (HSDD) and erectile dysfunction by acting centrally on the brain rather than peripherally on blood vessels. Unlike PDE5 inhibitors, PT-141 works through the central nervous system to increase sexual desire and arousal in both men and women.

0 RCT · 0 human · 0 preclinical

sexual

Retatrutide

Clinical

Triple-action metabolic optimization

Burn fat faster while feeling less hungry.

0 RCT · 0 human · 0 preclinical

fat-loss

Semaglutide

Clinical

GLP-1 receptor agonist for appetite suppression

A GLP-1 receptor agonist approved for type 2 diabetes management and chronic weight management, demonstrating substantial and sustained weight reduction in large clinical trials.

0 RCT · 0 human · 0 preclinical

fat-loss

Triptorelin Acetate

Clinical

GnRH analogue for hormonal axis modulation

Triptorelin Acetate is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) used clinically to treat hormone-sensitive conditions such as prostate cancer, endometriosis, and central precocious puberty. Upon initial administration it causes a transient surge in luteinizing hormone (LH) and follicle-stimulating hormone (FSH), followed by sustained suppression of gonadal steroid production through pituitary receptor desensitization. In research and off-label contexts, single low-dose administration has been explored as a means to transiently restore hypothalamic-pituitary-gonadal (HPG) axis function in individuals with post-anabolic-steroid-induced hypogonadism.

0 RCT · 0 human · 0 preclinical

sexual

Acetyl Hexapeptide-3 (Argireline)

Human-limited

Acetyl hexapeptide for expression lines

Topical neuropeptide for dynamic wrinkle reduction.

0 RCT · 0 human · 0 preclinical

skin

Acetyl Tetrapeptide-5 (Eyeseryl)

Human-limited

Acetyl tetrapeptide-5 for eye area

Under-eye peptide for puffiness reduction.

0 RCT · 0 human · 0 preclinical

skin

AHK-Cu

Human-limited

Copper peptide for skin regeneration and repair

AHK-Cu is a copper-binding tripeptide (Ala-His-Lys) complexed with copper(II) ions, closely related to the well-studied GHK-Cu peptide. It stimulates collagen and glycosaminoglycan synthesis in skin fibroblasts while exerting antioxidant and anti-inflammatory activity. Primarily researched in the context of skin regeneration, wound healing, and hair follicle stimulation.

0 RCT · 0 human · 0 preclinical

skin

AICAR

Human-limited

AMPK activator mimicking endurance exercise effects

AICAR (Acadesine) is a nucleoside analog and potent AMPK activator that mimics the cellular energy-depletion state, triggering a cascade of metabolic adaptations including enhanced fatty acid oxidation and mitochondrial biogenesis. It has been extensively studied for its ability to improve endurance performance, insulin sensitivity, and metabolic flexibility without physical exercise. Originally developed as a cardioprotective agent, it has attracted significant interest in the performance and longevity research communities.

0 RCT · 0 human · 0 preclinical

metabolic

Amlexanox (Peptide analog)

Human-limited

Tripeptide analog for mucosal inflammation

Anti-inflammatory peptide for canker sores and gut health.

0 RCT · 0 human · 0 preclinical

gut

AOD9604

Human-limited

Fat-targeting hGH fragment for metabolic support

AOD9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (amino acids 176–191), developed originally by Monash University as an anti-obesity drug. It mimics the lipolytic (fat-burning) effects of growth hormone without stimulating IGF-1 production or promoting cell proliferation. Research suggests it stimulates fat breakdown and inhibits fat formation, with a favorable safety profile compared to full-length hGH.

0 RCT · 0 human · 0 preclinical

fat-loss

ARA290 (Cibinetide)

Human-limited

Tissue-protective peptide for nerve repair and inflammation

ARA290, also known as Cibinetide, is a synthetic 11-amino acid peptide derived from the helix B surface peptide of erythropoietin (EPO) that selectively activates the innate repair receptor (IRR) without stimulating erythropoiesis. It is designed to harness the tissue-protective and anti-inflammatory properties of EPO while avoiding its hematopoietic side effects. Clinically, it has been investigated for neuropathic pain, small fiber neuropathy, and inflammatory conditions such as sarcoidosis.

0 RCT · 0 human · 0 preclinical

Immune

Biopeptide CL (Palmitoyl Oligopeptide)

Human-limited

Palmitoyl oligopeptide for collagen synthesis

Collagen-boosting peptide for firming and lifting.

0 RCT · 0 human · 0 preclinical

skin

BPC-157 (Recovery)

Human-limited

Pentadecapeptide for rapid recovery from injury

Body protection compound for tissue repair & recovery acceleration.

0 RCT · 0 human · 0 preclinical

Recovery

Cardiogen

Human-limited

Cardiac peptide bioregulator for heart longevity

Cardiogen is a short synthetic tetrapeptide (Ala-Glu-Asp-Arg) originally developed by the St. Petersburg Institute of Bioregulation and Gerontology in Russia, designed to support cardiac tissue health and function. It acts as a cytoprotective bioregulator targeting cardiomyocytes, promoting cellular repair and reducing age-related deterioration in heart muscle tissue. Research, primarily from Russian preclinical and limited clinical studies, suggests it may help maintain cardiac contractility, reduce fibrosis, and support overall cardiovascular resilience.

0 RCT · 0 human · 0 preclinical

Cardiovascular

Carnosine (beta-alanyl-L-histidine)

Human-limited

Natural anti-glycation and antioxidant dipeptide

Natural dipeptide for anti-glycation & cellular protection.

0 RCT · 0 human · 0 preclinical

longevity

Ceramide Peptide (Hexapeptide-11)

Human-limited

Hexapeptide for ceramide synthesis and barrier repair

Ceramide-boosting peptide for skin barrier repair.

0 RCT · 0 human · 0 preclinical

skin

CJC-1295

Human-limited

Long-acting GHRH analog for GH elevation

A long-acting GHRH analog that extends the half-life of endogenous growth hormone releasing hormone, producing sustained elevation of GH and IGF-1.

0 RCT · 0 human · 0 preclinical

growth

CJC-1295 (No DAC) + Ipamorelin 5mg Blend

Human-limited

Synergistic GH pulse amplifier for body and recovery

CJC-1295 (without DAC) + Ipamorelin is a synergistic peptide blend combining a growth hormone-releasing hormone (GHRH) analogue with a selective growth hormone secretagogue. Together, they stimulate the pituitary gland to release growth hormone in a pulsatile, physiologically natural manner. This combination is widely used for body composition improvement, recovery, anti-aging, and sleep quality enhancement.

0 RCT · 0 human · 0 preclinical

growth

CJC-1295 (Without DAC)

Human-limited

Natural GH Pulses for Growth and Recovery

CJC-1295 without DAC (also known as Modified GRF 1-29) is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to release growth hormone in a pulsatile, physiologically natural pattern. It consists of the first 29 amino acids of GHRH with four key amino acid substitutions that enhance stability and receptor affinity compared to the native peptide. It is widely used in research settings for its potential to promote lean muscle growth, fat loss, recovery, and anti-aging effects.

0 RCT · 0 human · 0 preclinical

growth

CJC-1295 with DAC

Human-limited

Long-acting GHRH analog for sustained GH release

CJC-1295 with DAC is a synthetic, long-acting analog of growth hormone-releasing hormone (GHRH) that incorporates a Drug Affinity Complex (DAC) to dramatically extend its half-life. By binding covalently to serum albumin, it maintains sustained elevation of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) for up to two weeks per injection. It is used in research settings to study GH secretion, body composition changes, and recovery processes.

0 RCT · 0 human · 0 preclinical

growth

Collagen peptides (Hydrolyzed Collagen)

Human-limited

Hydrolyzed collagen for structural support

Hydrolyzed collagen for skin, joint & bone support.

0 RCT · 0 human · 0 preclinical

skin

Copper Tripeptide-1 (GHK-Cu Injectable)

Human-limited

Systemic copper tripeptide for whole-body rejuvenation

Injectable copper peptide for systemic tissue repair.

0 RCT · 0 human · 0 preclinical

longevity

Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-ake)

Human-limited

Snake venom analog for expression lines

Snake venom-like peptide for dynamic wrinkle relaxation.

0 RCT · 0 human · 0 preclinical

skin

Dulaglutide

Human-limited

Long-acting GLP-1 receptor agonist

Weekly GLP-1 agonist for diabetes & weight management.

0 RCT · 0 human · 0 preclinical

fat-loss

Exenatide

Human-limited

Synthetic exendin-4 GLP-1 agonist

Exendin-4 synthetic peptide for glycemic control.

0 RCT · 0 human · 0 preclinical

fat-loss

GHK-Cu

Human-limited

Cellular rejuvenation & collagen synthesis

A naturally occurring copper-binding tripeptide found in human plasma that declines with age, known for its regenerative, anti-inflammatory, and gene-regulatory properties.

0 RCT · 0 human · 0 preclinical

skin

GHK-Cu (Recovery)

Human-limited

Copper tripeptide for recovery and repair

Copper peptide for tissue remodeling & recovery.

0 RCT · 0 human · 0 preclinical

Recovery

GHK-Cu (Topical)

Human-limited

Topical copper peptide for wound repair

Copper tripeptide for accelerated wound healing & scar reduction.

0 RCT · 0 human · 0 preclinical

healing

GHRP-2

Human-limited

Potent GH secretagogue for muscle and recovery

Growth hormone releasing peptide-2 for lean mass & recovery.

0 RCT · 0 human · 0 preclinical

growth

Glutathione

Human-limited

Master antioxidant for detox and cellular defense

Glutathione is a tripeptide antioxidant composed of glutamate, cysteine, and glycine that is naturally synthesized in virtually every cell of the body. It serves as the body's master antioxidant, neutralizing reactive oxygen species, supporting detoxification pathways, and maintaining redox homeostasis. Declining glutathione levels are associated with aging, chronic disease, and oxidative stress-related conditions.

0 RCT · 0 human · 0 preclinical

Immune

Gonadorelin

Human-limited

Gonadotropin-releasing hormone agonist

GnRH analog for fertility and hormonal assessment.

0 RCT · 0 human · 0 preclinical

sexual

Hexapeptide-9 (Vaccinium Myrtillus Peptide)

Human-limited

Bilberry-derived peptide for pigmentation

Antioxidant peptide for dark spots and photoaging.

0 RCT · 0 human · 0 preclinical

skin

Hexarelin

Human-limited

Potent growth hormone releasing peptide

Potent GH secretagogue with cardioprotective effects.

0 RCT · 0 human · 0 preclinical

growth

Hexarelin Acetate

Human-limited

Potent GH secretagogue with cardiac benefits

Hexarelin Acetate is a synthetic hexapeptide and potent growth hormone secretagogue (GHS) that stimulates pituitary release of growth hormone (GH) by mimicking the action of ghrelin. It binds to the GHS-R1a receptor with high affinity and also exhibits direct cardioprotective effects independent of GH release. Developed originally as a potential treatment for GH deficiency, it is one of the most potent GH-releasing peptides studied in clinical research.

0 RCT · 0 human · 0 preclinical

growth

HGH Fragment 176-191

Human-limited

Targeted fat-loss fragment of growth hormone

HGH Fragment 176-191 is a synthetic peptide derived from amino acids 176–191 of the C-terminus of human growth hormone (hGH). It was specifically engineered to retain the lipolytic (fat-burning) properties of hGH while eliminating its growth-promoting and insulin-desensitizing effects. Research, primarily in animal models, suggests it stimulates fat breakdown and inhibits the formation of new fat cells.

0 RCT · 0 human · 0 preclinical

fat-loss

Ipamorelin

Human-limited

GH-releasing peptide for lean mass and recovery

A selective growth hormone secretagogue and ghrelin mimetic that stimulates pituitary GH release with high specificity and minimal effect on cortisol or prolactin.

0 RCT · 0 human · 0 preclinical

growth

Kisspeptin-10

Human-limited

Endogenous HPG axis activator for sexual health

Kisspeptin-10 is the biologically active C-terminal decapeptide fragment of the larger kisspeptin precursor protein, encoded by the KISS1 gene. It acts as a potent endogenous activator of the hypothalamic-pituitary-gonadal (HPG) axis, stimulating the release of gonadotropin-releasing hormone (GnRH) and downstream luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It is investigated for applications in reproductive endocrinology, sexual function, and mood regulation.

0 RCT · 0 human · 0 preclinical

sexual

Lactoferrin

Human-limited

Iron-binding protein for immunity and gut barrier

Iron-binding glycoprotein for immune & gut health.

0 RCT · 0 human · 0 preclinical

Immune

Leuprolide (Lupron)

Human-limited

Long-acting GnRH agonist for hormone therapy

Long-acting GnRH agonist for hormone suppression.

0 RCT · 0 human · 0 preclinical

sexual

Lipo-C

Human-limited

Lipotropic blend for fat loss and liver health

Lipo-C is a lipotropic injection blend combining several compounds—typically methionine, inositol, choline, carnitine, and B vitamins—designed to support fat metabolism and liver function. It promotes the mobilization and breakdown of fat deposits, particularly in the liver. The formulation is commonly used in weight loss programs to enhance lipolysis and improve metabolic efficiency.

0 RCT · 0 human · 0 preclinical

fat-loss

Liraglutide

Human-limited

GLP-1 analog for daily weight management

Short-acting GLP-1 agonist for weight loss & diabetes.

0 RCT · 0 human · 0 preclinical

fat-loss

Lixisenatide

Human-limited

Short-acting GLP-1 for post-meal control

Short-acting GLP-1 agonist for post-meal glucose.

0 RCT · 0 human · 0 preclinical

fat-loss

LL-37

Human-limited

Human antimicrobial peptide for immunity and healing

LL-37 is a 37-amino acid human host defense peptide derived from the cathelicidin family, naturally produced by neutrophils, epithelial cells, and macrophages. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and viruses while simultaneously modulating immune responses and promoting wound healing. Research suggests it plays a critical role in innate immunity and may have therapeutic applications in chronic infections, wound repair, and inflammatory conditions.

0 RCT · 0 human · 0 preclinical

Immune

Melanotan II

Human-limited

Potent tanning and libido melanocortin agonist

Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) originally developed at the University of Arizona. It potently activates melanocortin receptors to stimulate skin tanning, increase sexual arousal, and suppress appetite. Unlike natural α-MSH, its cyclic structure confers greater receptor affinity and metabolic stability.

0 RCT · 0 human · 0 preclinical

skin

NAD+ (Nicotinamide Riboside)

Human-limited

NAD+ precursor for cellular energy and repair

NAD+ precursor for cellular energy & DNA repair.

0 RCT · 0 human · 0 preclinical

Mitochondrial

Oligopeptide-177 (Blue Peptide)

Human-limited

Marine-derived oligopeptide for moisture

Ocean-derived peptide for hydration and barrier repair.

0 RCT · 0 human · 0 preclinical

skin

Ornithine Alpha-Ketoglutarate (OKG)

Human-limited

Dipeptide for nitrogen retention and muscle recovery

Dipeptide precursor for muscle protein synthesis.

0 RCT · 0 human · 0 preclinical

growth

Palmitoyl Pentapeptide-4 (Matrixyl)

Human-limited

Palmitoyl pentapeptide for collagen signaling

Topical signaling peptide for collagen synthesis & anti-wrinkle.

0 RCT · 0 human · 0 preclinical

skin

Palmitoyl Tetrapeptide-7 (Rigin variant)

Human-limited

Palmitoylated tetrapeptide-7 for skin repair

Lipopeptide for collagen repair and anti-inflammation.

0 RCT · 0 human · 0 preclinical

longevity

Palmitoyl Tripeptide-1 (Pal-GHK)

Human-limited

Palmitoyl tripeptide-1 for skin repair

Topical signaling peptide for collagen & wound healing.

0 RCT · 0 human · 0 preclinical

skin

Pentapeptide-18 (Leuphasyl)

Human-limited

Leu-enkephalin analog for expression lines

Topical neuropeptide for gentle muscle relaxation.

0 RCT · 0 human · 0 preclinical

skin

Pentosan Polysulfate (PPS)

Human-limited

Polysulfated xylopyranose for cartilage and interstitial cystitis

Semi-synthetic peptide for osteoarthritis & bladder health.

0 RCT · 0 human · 0 preclinical

joint

PT-141 (Bremelanotide)

Human-limited

Melanocortin receptor agonist for sexual function

Melanocortin agonist for sexual health & libido.

0 RCT · 0 human · 0 preclinical

sexual

PTH (1-34) Teriparatide

Human-limited

Parathyroid hormone analog for bone building

Parathyroid hormone analog for severe osteoporosis anabolic therapy.

0 RCT · 0 human · 0 preclinical

Bone

Selank

Human-limited

Anxiolytic peptide for calm focus and immune support

A synthetic heptapeptide derived from the immunomodulatory peptide tuftsin, developed in Russia for anxiolytic and nootropic effects without the sedation or dependence of benzodiazepines.

0 RCT · 0 human · 0 preclinical

cognition

Semaglutide (Liver Health)

Human-limited

GLP-1 agonist for non-alcoholic fatty liver disease

GLP-1 agonist for fatty liver & metabolic health.

0 RCT · 0 human · 0 preclinical

liver

Snap-8

Human-limited

Peptide wrinkle relaxer targeting neuromuscular signaling

Snap-8 is a synthetic octapeptide cosmetic active designed to reduce the appearance of expression lines and wrinkles by modulating neuromuscular signaling at the dermal-muscle interface. It is an extended analog of Argireline (Acetyl Hexapeptide-3) with two additional amino acids, offering purportedly enhanced efficacy. Originally developed for topical cosmetic application, it has also been explored in research-grade injectable formulations for more direct tissue delivery.

0 RCT · 0 human · 0 preclinical

skin

Tesamorelin

Human-limited

FDA-approved GHRH analog for fat reduction

GHRH analog for visceral fat reduction & GH elevation.

0 RCT · 0 human · 0 preclinical

fat-loss

Tetrapeptide-30 (Skin Tightener)

Human-limited

Tetrapeptide for immediate and lasting firming

Instant tightening & long-term lifting peptide.

0 RCT · 0 human · 0 preclinical

skin

Tetrapeptide-7 (Rigin)

Human-limited

Tetrapeptide-7 for extracellular matrix repair

Anti-inflammatory peptide for skin rejuvenation.

0 RCT · 0 human · 0 preclinical

longevity

Thymalin/Thymulin

Human-limited

Thymic peptide restoring immune vitality with age

Thymalin is a thymic peptide preparation derived from calf thymus glands, while Thymulin (FTS) is a naturally occurring nonapeptide produced by thymic epithelial cells that requires zinc as a cofactor for biological activity. Together they represent thymic-origin immunomodulatory compounds that restore and regulate T-lymphocyte differentiation, maturation, and function. They are used primarily to support immune system integrity, combat immunosenescence, and may have applications in anti-aging and recovery protocols.

0 RCT · 0 human · 0 preclinical

Immune

Thymosin Alpha-1

Human-limited

Thymus peptide for lung immune defense

Thymus peptide for immune modulation & respiratory health.

0 RCT · 0 human · 0 preclinical

Respiratory

Thymosin Alpha-1

Human-limited

Thymus peptide for immune system enhancement

Immune modulator for T-cell enhancement & infection support.

0 RCT · 0 human · 0 preclinical

Immune

Tirzepatide

Human-limited

Dual GIP/GLP-1 receptor agonist

Dual GIP/GLP-1 agonist for superior weight loss & glycemic control.

0 RCT · 0 human · 0 preclinical

fat-loss

Tripeptide-1 (Growth Factor Fragment)

Human-limited

Growth factor mimetic for skin and hair

Growth factor mimetic for skin rejuvenation.

0 RCT · 0 human · 0 preclinical

skin

Acetyl Tetrapeptide-3 (Darnosine)

Animal

Acetyl tetrapeptide-3 for AGE prevention

Advanced AGE-breaker for deep anti-wrinkle action.

0 RCT · 0 human · 0 preclinical

longevity

Adipotide (FTTP)

Animal

Targeted fat-depot destruction via vascular apoptosis

Adipotide (also called FTTP) is an experimental peptidomimetic compound designed to selectively destroy the blood supply to white adipose tissue by targeting prohibitin, a protein highly expressed on the vasculature feeding fat cells. Originally developed at MD Anderson Cancer Center, it demonstrated dramatic fat loss in obese rhesus monkeys without dietary restriction. It remains a research compound with no approved human clinical use.

0 RCT · 0 human · 0 preclinical

fat-loss

ARA-290 (Cibinetide)

Animal

Erythropoietin analog for kidney protection

Erythropoietin-derived peptide for kidney & nerve protection.

0 RCT · 0 human · 0 preclinical

kidney

B7-33

Animal

Biased RXFP1 agonist for cardiac fibrosis

B7-33 is a single-chain peptide analog of human relaxin-2, engineered to selectively activate the RXFP1 receptor without triggering the cAMP signaling pathway. It demonstrates potent anti-fibrotic, vasodilatory, and cardioprotective effects in preclinical models. Research primarily focuses on its potential in heart failure, pulmonary arterial hypertension, and organ fibrosis.

0 RCT · 0 human · 0 preclinical

Cardiovascular

BPC-157

Animal

Systemic healing for wounds, tendons, and gut

A synthetic pentadecapeptide derived from a protein in gastric juice, studied for tissue repair, gut protection, and musculoskeletal healing.

0 RCT · 0 human · 0 preclinical

healing

BPC-157 (Liver)

Animal

Pentadecapeptide for liver protection

Body protection compound for liver detoxification & repair.

0 RCT · 0 human · 0 preclinical

liver

BPC-157 + TB-500 Blend (10mg + 10mg)

Animal

Synergistic healing and recovery peptide blend

BPC-157 + TB-500 is a pre-mixed peptide blend combining Body Protection Compound-157 (a gastric pentadecapeptide) and Thymosin Beta-4 fragment (TB-500) into a single vial for convenience. Together, these two peptides target overlapping and complementary pathways in tissue repair, angiogenesis, and inflammation modulation. The combination is widely used in the research and biohacking communities for accelerated musculoskeletal recovery, tendon and ligament healing, and systemic anti-inflammatory effects.

0 RCT · 0 human · 0 preclinical

Recovery

BPC-157 + TB-500 Blend (5mg + 5mg)

Animal

Synergistic repair blend for accelerated healing

BPC-157 + TB-500 is a synergistic peptide blend combining Body Protection Compound-157 (5mg) and Thymosin Beta-4 fragment TB-500 (5mg) into a single vial. BPC-157 is a synthetic pentadecapeptide derived from a protective gastric protein, while TB-500 is a synthetic analog of the actin-sequestering protein Thymosin Beta-4, both of which promote tissue repair and regeneration. Together, they are widely used in research for accelerated healing of musculoskeletal injuries, tendons, ligaments, and soft tissue damage.

0 RCT · 0 human · 0 preclinical

Recovery

Calcitonin (Salmon)

Animal

Salmon calcitonin for bone density

Calcium-regulating peptide for bone density & fracture prevention.

0 RCT · 0 human · 0 preclinical

Bone

Cerebrolysin

Animal

Neurotrophic peptide blend for cognitive repair

Neurotrophic peptide mix for brain repair & cognitive recovery.

0 RCT · 0 human · 0 preclinical

cognition

Cortagen

Animal

Pineal-derived peptide for brain and immunity

Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Pro) derived from the pineal gland and developed within the Russian peptide bioregulator program. It is primarily studied for its neuroprotective and immunomodulatory properties, with research suggesting it may support cortical function, slow age-related neurological decline, and modulate immune responses. Most of its evidence base comes from Russian preclinical and limited clinical studies conducted in the 1980s–2000s.

0 RCT · 0 human · 0 preclinical

cognition

Crystagen

Animal

Ocular cytoprotection via crystallin chaperone mimicry

Crystagen is a synthetic peptide derived from the alpha-crystallin protein family, small heat-shock proteins (sHSPs) naturally abundant in the eye lens. It is investigated primarily for its cytoprotective and anti-apoptotic properties in ocular tissues, with emerging research suggesting neuroprotective and anti-inflammatory effects. Evidence is largely limited to animal and in vitro models, and no approved clinical use currently exists.

0 RCT · 0 human · 0 preclinical

eye

Decapeptide-12 (Melanostatine-5)

Animal

Decapeptide for melanin reduction

Melanin-inhibiting peptide for hyperpigmentation.

0 RCT · 0 human · 0 preclinical

skin

Dermorphin

Animal

Ultra-potent frog-derived mu-opioid peptide

Dermorphin is a naturally occurring heptapeptide opioid first isolated from the skin secretions of South American phyllomedusa frogs. It binds with extraordinarily high selectivity and affinity to mu-opioid receptors, producing potent analgesic and sedative effects estimated to be 30–40 times more potent than morphine on a molar basis. Its unique structure incorporates a D-amino acid (D-Ala), which confers resistance to enzymatic degradation and prolongs its biological activity.

0 RCT · 0 human · 0 preclinical

mood

Dermorphin

Animal

Potent frog-derived mu-opioid receptor agonist

Dermorphin is a naturally occurring heptapeptide opioid first isolated from the skin of South American Phyllomedusa frogs. It binds with extraordinarily high selectivity and potency to mu-opioid receptors, producing analgesic effects estimated to be 30–40 times more potent than morphine on a molar basis. Research has primarily been conducted in animal models, with extremely limited controlled human data available.

0 RCT · 0 human · 0 preclinical

mood

DSIP (Delta Sleep-Inducing Peptide)

Animal

Delta sleep-inducing peptide for deep sleep

Natural peptide for deep sleep induction & stress reduction.

0 RCT · 0 human · 0 preclinical

sleep

Epitalon

Animal

Pineal tetrapeptide for sleep and rhythm

A synthetic tetrapeptide derived from Epithalamin (a pineal gland extract) that has been studied for telomere elongation, circadian rhythm normalization, and lifespan extension in animal models.

0 RCT · 0 human · 0 preclinical

longevity

Epithalon

Animal

Extend your cellular lifespan

A synthetic tetrapeptide that activates telomerase — the enzyme that protects your chromosomes from aging.

0 RCT · 0 human · 0 preclinical

longevity

FOXO4-DRI

Animal

Senolytic peptide targeting cellular senescence

FOXO4-DRI is a D-amino acid retro-inverso peptide designed to selectively induce apoptosis in senescent cells by disrupting the interaction between FOXO4 and p53. It belongs to a class of experimental senolytic compounds—agents that clear aged, dysfunctional 'zombie' cells from tissues. Research has been conducted primarily in mouse models, where it demonstrated improvements in fitness, fur density, kidney function, and lifespan metrics.

0 RCT · 0 human · 0 preclinical

longevity

FST 344

Animal

Myostatin blocker for serious muscle hypertrophy

FST 344 is a recombinant isoform of follistatin, a naturally occurring glycoprotein that binds and neutralizes myostatin and activin, two potent inhibitors of muscle growth. By suppressing these negative regulators, FST 344 promotes skeletal muscle hypertrophy, enhances recovery, and may support bone density. It has been investigated in gene therapy and preclinical contexts for muscular dystrophy and sarcopenia, though human clinical data remain very limited.

0 RCT · 0 human · 0 preclinical

growth

FTPP Adipotide

Animal

Targeted fat-depot elimination via vascular apoptosis

Adipotide is a pro-apoptotic peptidomimetic designed to selectively destroy the blood supply feeding white adipose tissue (WAT), causing fat cell death through targeted vascular disruption. It was developed at MD Anderson Cancer Center primarily as an anti-obesity compound and has shown dramatic fat loss in non-human primate studies. Human clinical data remains extremely limited, and it is considered a research compound only.

0 RCT · 0 human · 0 preclinical

fat-loss

GDF-8 (Myostatin)

Animal

The Master Brake on Muscle Growth

GDF-8, also known as myostatin, is a TGF-β superfamily member that acts as a potent negative regulator of skeletal muscle mass. It limits muscle fiber size and number by inhibiting myoblast proliferation and differentiation. Research into myostatin inhibition has generated significant interest for applications in muscle wasting diseases, metabolic disorders, and athletic performance.

0 RCT · 0 human · 0 preclinical

growth

GHRP-3

Animal

Third-generation GH secretagogue with refined selectivity

GHRP-3 is a synthetic hexapeptide and member of the growth hormone releasing peptide family, designed to stimulate the pulsatile release of growth hormone (GH) from the anterior pituitary gland. It acts primarily as a ghrelin mimetic and GHS-R1a agonist, amplifying natural GH secretion pulses. GHRP-3 is structurally related to GHRP-2 and GHRP-6 but exhibits a modified amino acid sequence intended to reduce appetite-stimulating side effects while maintaining GH secretagogue potency.

0 RCT · 0 human · 0 preclinical

growth

GHRP-6

Animal

GH-releasing peptide with orexigenic effects

Growth hormone releasing peptide with appetite stimulation.

0 RCT · 0 human · 0 preclinical

growth

GLOW (BPC-157 + GHK-Cu + TB-500 Blend)

Animal

Regenerate, Renew, Glow From Within

GLOW is a synergistic peptide blend combining BPC-157 (10mg), GHK-Cu (50mg), and TB-500 (10mg) into a single formulation designed to accelerate tissue repair, promote skin rejuvenation, and support systemic recovery. BPC-157 and TB-500 target musculoskeletal and gut healing, while GHK-Cu drives collagen synthesis, anti-inflammatory signaling, and skin remodeling. Together, these three peptides work across complementary pathways to produce enhanced regenerative and cosmetic outcomes.

0 RCT · 0 human · 0 preclinical

healing

GLP-1 (7-36) Amide

Animal

Endogenous GLP-1 for meal-time satiety

Native GLP-1 peptide for acute appetite control.

0 RCT · 0 human · 0 preclinical

fat-loss

IGF-1 LR3

Animal

Long-R3 insulin-like growth factor for muscle differentiation

Long-acting IGF-1 analog for muscle growth & differentiation.

0 RCT · 0 human · 0 preclinical

growth

KPV

Animal

Tripeptide for intestinal inflammation reduction

Alpha-MSH fragment for gut-specific anti-inflammatory effects.

0 RCT · 0 human · 0 preclinical

gut

Mechano Growth Factor (MGF)

Animal

Local muscle repair signal for accelerated recovery

Mechano Growth Factor (MGF) is a splice variant of Insulin-like Growth Factor 1 (IGF-1) that is produced locally in muscle and other tissues in response to mechanical stress or damage. It plays a critical role in activating satellite cells (muscle stem cells) to initiate repair and hypertrophy. MGF is primarily of interest to researchers studying muscle regeneration, athletic recovery, and tissue repair.

0 RCT · 0 human · 0 preclinical

growth

Melanotan I (Melanotan-1)

Animal

Selective melanocortin-1 receptor agonist

Selective MC1-R agonist for UV-free tanning.

0 RCT · 0 human · 0 preclinical

skin

Melanotan II

Animal

Melanocortin agonist for tanning and sexual function

Melanocortin peptide for tanning & libido enhancement.

0 RCT · 0 human · 0 preclinical

skin

Myristoyl Pentapeptide-17 (Keratinocyte Growth Factor Fragment)

Animal

Myristoyl pentapeptide for hair stimulation

Keratinocyte-stimulating peptide for hair growth.

0 RCT · 0 human · 0 preclinical

skin

Oligopeptide-68 (Progeline)

Animal

Oligopeptide-68 for cellular aging reversal

Anti-senescence peptide that reduces progerin.

0 RCT · 0 human · 0 preclinical

longevity

Orexin B

Animal

Wakefulness neuropeptide driving arousal and cognition

Orexin B (also known as Hypocretin-2) is a neuropeptide produced in the lateral hypothalamus that plays a central role in regulating wakefulness, arousal, appetite, and energy homeostasis. It acts primarily through the OX2 receptor (orexin receptor type 2) to promote and maintain wakefulness and modulate feeding behavior. Research into orexin B is largely preclinical, but it has significant implications for understanding narcolepsy, sleep disorders, and metabolic regulation.

0 RCT · 0 human · 0 preclinical

sleep

PE-22-28

Animal

Novel TREK-1 inhibitor for mood and cognition

PE-22-28 is a synthetic peptide analog derived from the propeptide of neurotensin (also related to the TREK-1 channel inhibitor spadin), engineered to inhibit TREK-1 potassium channels in the brain. It has demonstrated rapid antidepressant-like effects in preclinical rodent models, often acting faster than conventional antidepressants. Research interest is growing due to its novel mechanism and potential to address treatment-resistant depression.

0 RCT · 0 human · 0 preclinical

mood

Pentadecapeptide BPC-157 (Oral Stable)

Animal

Oral-stable pentadecapeptide for GI repair

Gut-stable oral BPC-157 for digestive healing.

0 RCT · 0 human · 0 preclinical

gut

Peptide YY (PYY 3-36)

Animal

Endogenous Y2 receptor agonist for satiety

Natural appetite-suppressing gut peptide.

0 RCT · 0 human · 0 preclinical

fat-loss

Pinealon

Animal

Pineal tripeptide for better sleep

Pineal peptide for circadian rhythm & sleep quality improvement.

0 RCT · 0 human · 0 preclinical

sleep

PNC-27

Animal

Selective cancer cell membrane-targeting peptide

PNC-27 is a synthetic peptide derived from the p53 tumor suppressor protein, designed to selectively induce apoptosis in cancer cells while leaving normal cells unharmed. It contains an MDM-2-binding domain of p53 fused to a transmembrane-penetrating sequence, enabling it to insert into the membranes of cancer cells that aberrantly express HDM-2 on their surface. Research has been conducted primarily in vitro and in animal models, with very limited human data available.

0 RCT · 0 human · 0 preclinical

Immune

Semax

Animal

Nootropic ACTH analog for cognitive enhancement

Nootropic peptide for memory, focus & neuroprotection.

0 RCT · 0 human · 0 preclinical

cognition

SLU-PP-322

Animal

Exercise mimetic targeting mitochondrial energy pathways

SLU-PP-322 is a synthetic small-molecule agonist of estrogen-related receptors (ERRα, ERRβ, and ERRγ) developed at Saint Louis University. It mimics the metabolic effects of sustained aerobic exercise at the cellular level, promoting mitochondrial biogenesis, fatty acid oxidation, and endurance capacity without physical activity. In preclinical animal studies, it has demonstrated significant improvements in exercise performance, fat metabolism, and cardiac function.

0 RCT · 0 human · 0 preclinical

Mitochondrial

SS-31 (Elamipretide)

Animal

Mitochondrial peptide for renal protection

Mitochondrial-targeted peptide for kidney & metabolic protection.

0 RCT · 0 human · 0 preclinical

kidney

SS-31 (Elamipretide)

Animal

Mitochondrial peptide for metabolic and renal health

Mitochondrial-targeted peptide for metabolic & kidney protection.

0 RCT · 0 human · 0 preclinical

metabolic

TB-500

Animal

Thymosin beta-4 fragment for wound repair

A synthetic fragment of Thymosin Beta-4, a naturally occurring protein involved in actin regulation, tissue repair, and inflammation modulation.

0 RCT · 0 human · 0 preclinical

healing

TB-500

Animal

Accelerate healing, reduce inflammation, restore mobility

TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4, a naturally occurring protein found in virtually all human and animal cells. It promotes tissue repair, reduces inflammation, and accelerates healing of muscles, tendons, ligaments, and skin. It is widely used in research and sports recovery contexts for its potent regenerative properties.

0 RCT · 0 human · 0 preclinical

Recovery

TB-500 (Recovery)

Animal

Thymosin beta-4 for injury recovery

Thymosin beta-4 for systemic recovery & inflammation reduction.

0 RCT · 0 human · 0 preclinical

Recovery

Tetrapeptide-21 (Ganirelix analog)

Animal

Tetrapeptide for hair follicle activation

Hair growth peptide for follicle stimulation.

0 RCT · 0 human · 0 preclinical

skin

Tetrapeptide-68 (Adifyline)

Animal

Tetrapeptide for facial fat restoration

Adipogenesis peptide for facial volume restoration.

0 RCT · 0 human · 0 preclinical

skin

Thymulin

Animal

Thymus peptide for respiratory immune balance

Thymus peptide for immune balance & lung protection.

0 RCT · 0 human · 0 preclinical

Respiratory

Thymulin

Animal

Thymus peptide for immune modulation

Thymus peptide for immune balance & T-cell maturation.

0 RCT · 0 human · 0 preclinical

Immune

Vasopressin (ADH analog)

Animal

Antidiuretic hormone peptide

Antidiuretic hormone for water retention & blood pressure.

0 RCT · 0 human · 0 preclinical

Cardiovascular

Vilon

Animal

Thymus dipeptide for immune and DNA health

Thymus dipeptide for immune restoration & DNA repair.

0 RCT · 0 human · 0 preclinical

Immune

VIP (Vasoactive Intestinal Peptide)

Animal

Vasoactive intestinal peptide for ocular health

Neuroprotective peptide for dry eye & retinal health.

0 RCT · 0 human · 0 preclinical

eye

Ziconotide (MVIIA ω-conotoxin)

Animal

Conotoxin analog for intractable pain

Conopeptide for severe intrathecal pain management.

0 RCT · 0 human · 0 preclinical

cognition

ACE-031

Anecdotal

ACVR2B-Fc myostatin/activin trap

ACVR2B-Fc fusion protein for myostatin & activin inhibition.

0 RCT · 0 human · 0 preclinical

growth

Adamax

Anecdotal

Nootropic peptide blend for cognition and mood

Adamax is a research peptide blend reported to combine nootropic and neuroprotective peptide components aimed at enhancing cognitive function, mood stability, and neural recovery. It is marketed primarily for its potential effects on dopaminergic and serotonergic signaling pathways. Evidence is largely limited to preclinical and anecdotal sources, with no published human clinical trials specific to the Adamax formulation.

0 RCT · 0 human · 0 preclinical

cognition

AOD-9604

Anecdotal

HGH fragment for lipolysis stimulation

HGH fragment for localized fat metabolism.

0 RCT · 0 human · 0 preclinical

fat-loss

DauD2 (Defensin-like peptide)

Anecdotal

Antimicrobial defensin-like peptide

Antimicrobial & immune peptide for acne and infection.

0 RCT · 0 human · 0 preclinical

skin

Davunetide (AL-108)

Anecdotal

NAPVSIPQ peptide for microtubule stabilization

Neuroprotective peptide for tauopathies (Alzheimer's, PSP).

0 RCT · 0 human · 0 preclinical

cognition

Dihexa

Anecdotal

Hepatocyte growth factor agonist for neurogenesis

Potent neurogenic peptide for cognitive repair.

0 RCT · 0 human · 0 preclinical

cognition

Follistatin-344

Anecdotal

Myostatin antagonist for muscle hyperplasia

Myostatin inhibitor for extreme muscle growth.

0 RCT · 0 human · 0 preclinical

growth

FOXO4-DRI

Anecdotal

Senolytic peptide for cellular rejuvenation

Senolytic peptide that clears aged & damaged cells.

0 RCT · 0 human · 0 preclinical

longevity

Frag 17-23

Anecdotal

Experimental GH fragment targeting fat metabolism

Frag 17-23 is a short synthetic peptide fragment derived from amino acids 17 through 23 of the human growth hormone (hGH) sequence. It is hypothesized to retain lipolytic properties similar to larger hGH fragments while being structurally distinct from the more widely studied Frag 176-191. Evidence for its efficacy in humans remains largely anecdotal, with minimal published research specific to this fragment.

0 RCT · 0 human · 0 preclinical

fat-loss

GHRP-4

Anecdotal

Pituitary GH secretagogue for growth and recovery

GHRP-4 is a synthetic hexapeptide ghrelin mimetic designed to stimulate the pituitary gland's release of endogenous growth hormone. It belongs to the same family as GHRP-2 and GHRP-6 but is a less extensively characterized analog with a modified structure aimed at optimizing GH release with a potentially reduced appetite-stimulating side effect profile. Research on GHRP-4 specifically is limited compared to its better-studied relatives, and most mechanistic understanding is extrapolated from the broader GHRP class.

0 RCT · 0 human · 0 preclinical

growth

Humanin

Anecdotal

Mitochondrial peptide for brain protection

Mitochondrial-derived neuroprotective peptide.

0 RCT · 0 human · 0 preclinical

cognition

KLOW

Anecdotal

Electrolyte balance and cardiovascular metabolic support

KLOW is a research compound or proprietary peptide blend purported to support electrolyte balance, cardiovascular function, and cellular metabolic homeostasis. It is marketed within the peptide research space, though its precise composition and mechanism are not well-established in peer-reviewed literature. Evidence for its specific effects remains largely anecdotal and preclinical.

0 RCT · 0 human · 0 preclinical

metabolic

KPV-cyclo (cyclo-KPV)

Anecdotal

Cyclized KPV for IBD and gut inflammation

Cyclized KPV analog for enhanced gut stability.

0 RCT · 0 human · 0 preclinical

gut

LL-37

Anecdotal

Antimicrobial peptide for respiratory defense

Cathelicidin antimicrobial peptide for lung infection clearance.

0 RCT · 0 human · 0 preclinical

Respiratory

LL-37

Anecdotal

Cathelicidin peptide for innate immunity

Cathelicidin-derived antimicrobial & immune-modulating peptide.

0 RCT · 0 human · 0 preclinical

Immune

MOTS-c

Anecdotal

Mitochondrial-encoded peptide for glucose control

Mitochondrial-derived peptide for metabolic regulation & insulin sensitivity.

0 RCT · 0 human · 0 preclinical

metabolic

NAPVSIPQ (ADNP fragment)

Anecdotal

Active fragment of neuroprotective protein ADNP

Activity-dependent neuroprotective peptide fragment.

0 RCT · 0 human · 0 preclinical

cognition

PEG-MGF

Anecdotal

PEG-MGF for muscle hyperplasia and repair

PEGylated Mechano Growth Factor for muscle stem cell activation.

0 RCT · 0 human · 0 preclinical

growth

TGF-β1 Mimetic Peptide (Tetrapeptide-28)

Anecdotal

Tetrapeptide-28 for scarless healing

TGF-β1 mimicking peptide for scar reduction.

0 RCT · 0 human · 0 preclinical

healing

Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.