The library
149 compounds. Every one graded.
Filter by research area or by how strong the evidence actually is. Profiles graded Animal or Anecdotal are not hidden they are labelled, which is more useful.
- Clinical
- 15
- Human-limited
- 61
- Animal
- 54
- Anecdotal
- 19
149 of 149 profiles
ACTH 1-39
ClinicalFull-length adrenal hormone with broad receptor activity
ACTH 1-39 is the full-length, biologically active form of adrenocorticotropic hormone, a 39-amino acid peptide naturally secreted by the anterior pituitary gland. It primarily stimulates the adrenal cortex to produce cortisol, aldosterone, and adrenal androgens. Beyond adrenal signaling, ACTH 1-39 exerts direct effects on the brain, immune system, and peripheral tissues via melanocortin receptors.
0 RCT · 0 human · 0 preclinical
Immune
Cagrilintide
ClinicalOnce-weekly amylin analogue for weight loss
Cagrilintide is a long-acting acylated amylin analogue developed by Novo Nordisk for the treatment of obesity and type 2 diabetes. It mimics the pancreatic hormone amylin to reduce appetite, slow gastric emptying, and promote satiety. In clinical trials, it has been studied both as a monotherapy and in combination with semaglutide (as CagriSema), demonstrating meaningful and sustained body weight reduction.
0 RCT · 0 human · 0 preclinical
metabolic
Cagrisema (2.5mg + 2.5mg)
ClinicalDual amylin-GLP-1 therapy for superior weight loss
Cagrisema is a fixed-ratio combination of cagrilintide (a long-acting amylin analogue) and semaglutide (a GLP-1 receptor agonist), each at 2.5 mg per dose. This dual-hormone therapy is designed to provide additive and potentially synergistic effects on appetite suppression, glycemic control, and body weight reduction beyond what either agent achieves alone. It is currently under clinical investigation by Novo Nordisk for the treatment of obesity and type 2 diabetes.
0 RCT · 0 human · 0 preclinical
metabolic
Erythropoietin (EPO)
ClinicalOxygen-boosting hormone for endurance and anemia
Erythropoietin (EPO) is a glycoprotein hormone naturally produced primarily by the kidneys that regulates red blood cell production. Recombinant human EPO (rHuEPO) mimics this endogenous hormone to stimulate erythropoiesis in the bone marrow, increasing oxygen-carrying capacity. It is clinically approved for anemia associated with chronic kidney disease, chemotherapy, and certain other conditions, but is also widely misused as a performance-enhancing agent in endurance sports.
0 RCT · 0 human · 0 preclinical
Cardiovascular
Gonadorelin Acetate
ClinicalPreserve natural testosterone via HPG axis activation
Gonadorelin Acetate is a synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH), produced and secreted by the hypothalamus. It stimulates the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby supporting endogenous testosterone and estrogen production. It is used clinically to assess pituitary function, treat hypogonadism, support fertility, and is increasingly used alongside anabolic protocols to preserve testicular function.
0 RCT · 0 human · 0 preclinical
sexual
Human Chorionic Gonadotropin (HCG)
ClinicalThe LH Mimic for Hormonal Restoration
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced by the placenta during pregnancy, structurally similar to luteinizing hormone (LH). In clinical and research settings, it is used to stimulate testosterone production in men, support fertility, and maintain testicular function during or after anabolic steroid use. It acts directly on the gonads to mimic LH signaling, making it a cornerstone of hormonal restoration protocols.
0 RCT · 0 human · 0 preclinical
sexual
Human Growth Hormone (HGH)
ClinicalThe master anabolic and lipolytic growth hormone
Human Growth Hormone (HGH) is a 191-amino acid peptide hormone naturally secreted by the anterior pituitary gland that regulates growth, body composition, and metabolism. In clinical and performance contexts, recombinant HGH (rhGH) is administered exogenously to mimic or augment endogenous GH signaling. It is one of the most studied anabolic and lipolytic compounds in endocrinology, with established uses in GH deficiency, muscle-wasting conditions, and anti-aging protocols.
0 RCT · 0 human · 0 preclinical
growth
Human Menopausal Gonadotropin (HMG)
ClinicalDual gonadotropin for fertility and testicular function
Human Menopausal Gonadotropin (HMG) is a purified preparation of gonadotropins extracted from the urine of postmenopausal women, containing both Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) activity in approximately equal ratios. In clinical medicine it is used to stimulate ovulation in women and spermatogenesis in men, particularly those with hypogonadotropic hypogonadism. In performance and fertility contexts, HMG is used alongside or after hCG to restore or maintain testicular function, intratesticular testosterone production, and sperm output.
0 RCT · 0 human · 0 preclinical
sexual
Mazdutide
ClinicalDual GLP-1/glucagon agonist for metabolic health
Mazdutide is a dual GLP-1/glucagon receptor co-agonist peptide developed by Innovent Biologics, originally derived from oxyntomodulin. It simultaneously activates both GLP-1 and glucagon receptors to produce robust reductions in body weight, blood glucose, and hepatic fat. Clinical trials in China have demonstrated significant efficacy for obesity and type 2 diabetes management.
0 RCT · 0 human · 0 preclinical
metabolic
Melanotan I
ClinicalClinical-grade melanocyte activator for photoprotection
Melanotan I (afamelanotide) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that potently stimulates melanogenesis, increasing skin pigmentation without requiring UV exposure. It was developed primarily to protect individuals with photosensitive conditions such as erythropoietic protoporphyria (EPP) from painful phototoxic reactions. Beyond tanning, it has demonstrated anti-inflammatory, photoprotective, and potentially immunomodulatory effects in clinical and preclinical studies.
0 RCT · 0 human · 0 preclinical
skin
Oxytocin Acetate
ClinicalThe bonding hormone for trust and connection
Oxytocin Acetate is the acetate salt form of oxytocin, a naturally occurring nonapeptide hormone synthesized in the hypothalamus and released by the posterior pituitary gland. It plays central roles in social bonding, trust, stress reduction, sexual function, and uterine contraction. Research has expanded its potential applications to include anxiety reduction, prosocial behavior enhancement, and modulation of the hypothalamic-pituitary-adrenal (HPA) axis.
0 RCT · 0 human · 0 preclinical
mood
PT-141
ClinicalCentral nervous system sexual desire activator
PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist originally derived from the tanning peptide Melanotan II. It is used to treat hypoactive sexual desire disorder (HSDD) and erectile dysfunction by acting centrally on the brain rather than peripherally on blood vessels. Unlike PDE5 inhibitors, PT-141 works through the central nervous system to increase sexual desire and arousal in both men and women.
0 RCT · 0 human · 0 preclinical
sexual
Retatrutide
ClinicalTriple-action metabolic optimization
Burn fat faster while feeling less hungry.
0 RCT · 0 human · 0 preclinical
fat-loss
Semaglutide
ClinicalGLP-1 receptor agonist for appetite suppression
A GLP-1 receptor agonist approved for type 2 diabetes management and chronic weight management, demonstrating substantial and sustained weight reduction in large clinical trials.
0 RCT · 0 human · 0 preclinical
fat-loss
Triptorelin Acetate
ClinicalGnRH analogue for hormonal axis modulation
Triptorelin Acetate is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) used clinically to treat hormone-sensitive conditions such as prostate cancer, endometriosis, and central precocious puberty. Upon initial administration it causes a transient surge in luteinizing hormone (LH) and follicle-stimulating hormone (FSH), followed by sustained suppression of gonadal steroid production through pituitary receptor desensitization. In research and off-label contexts, single low-dose administration has been explored as a means to transiently restore hypothalamic-pituitary-gonadal (HPG) axis function in individuals with post-anabolic-steroid-induced hypogonadism.
0 RCT · 0 human · 0 preclinical
sexual
Acetyl Hexapeptide-3 (Argireline)
Human-limitedAcetyl hexapeptide for expression lines
Topical neuropeptide for dynamic wrinkle reduction.
0 RCT · 0 human · 0 preclinical
skin
Acetyl Tetrapeptide-5 (Eyeseryl)
Human-limitedAcetyl tetrapeptide-5 for eye area
Under-eye peptide for puffiness reduction.
0 RCT · 0 human · 0 preclinical
skin
AHK-Cu
Human-limitedCopper peptide for skin regeneration and repair
AHK-Cu is a copper-binding tripeptide (Ala-His-Lys) complexed with copper(II) ions, closely related to the well-studied GHK-Cu peptide. It stimulates collagen and glycosaminoglycan synthesis in skin fibroblasts while exerting antioxidant and anti-inflammatory activity. Primarily researched in the context of skin regeneration, wound healing, and hair follicle stimulation.
0 RCT · 0 human · 0 preclinical
skin
AICAR
Human-limitedAMPK activator mimicking endurance exercise effects
AICAR (Acadesine) is a nucleoside analog and potent AMPK activator that mimics the cellular energy-depletion state, triggering a cascade of metabolic adaptations including enhanced fatty acid oxidation and mitochondrial biogenesis. It has been extensively studied for its ability to improve endurance performance, insulin sensitivity, and metabolic flexibility without physical exercise. Originally developed as a cardioprotective agent, it has attracted significant interest in the performance and longevity research communities.
0 RCT · 0 human · 0 preclinical
metabolic
Amlexanox (Peptide analog)
Human-limitedTripeptide analog for mucosal inflammation
Anti-inflammatory peptide for canker sores and gut health.
0 RCT · 0 human · 0 preclinical
gut
AOD9604
Human-limitedFat-targeting hGH fragment for metabolic support
AOD9604 is a synthetic peptide fragment derived from the C-terminal region of human growth hormone (amino acids 176–191), developed originally by Monash University as an anti-obesity drug. It mimics the lipolytic (fat-burning) effects of growth hormone without stimulating IGF-1 production or promoting cell proliferation. Research suggests it stimulates fat breakdown and inhibits fat formation, with a favorable safety profile compared to full-length hGH.
0 RCT · 0 human · 0 preclinical
fat-loss
ARA290 (Cibinetide)
Human-limitedTissue-protective peptide for nerve repair and inflammation
ARA290, also known as Cibinetide, is a synthetic 11-amino acid peptide derived from the helix B surface peptide of erythropoietin (EPO) that selectively activates the innate repair receptor (IRR) without stimulating erythropoiesis. It is designed to harness the tissue-protective and anti-inflammatory properties of EPO while avoiding its hematopoietic side effects. Clinically, it has been investigated for neuropathic pain, small fiber neuropathy, and inflammatory conditions such as sarcoidosis.
0 RCT · 0 human · 0 preclinical
Immune
Biopeptide CL (Palmitoyl Oligopeptide)
Human-limitedPalmitoyl oligopeptide for collagen synthesis
Collagen-boosting peptide for firming and lifting.
0 RCT · 0 human · 0 preclinical
skin
BPC-157 (Recovery)
Human-limitedPentadecapeptide for rapid recovery from injury
Body protection compound for tissue repair & recovery acceleration.
0 RCT · 0 human · 0 preclinical
Recovery
Cardiogen
Human-limitedCardiac peptide bioregulator for heart longevity
Cardiogen is a short synthetic tetrapeptide (Ala-Glu-Asp-Arg) originally developed by the St. Petersburg Institute of Bioregulation and Gerontology in Russia, designed to support cardiac tissue health and function. It acts as a cytoprotective bioregulator targeting cardiomyocytes, promoting cellular repair and reducing age-related deterioration in heart muscle tissue. Research, primarily from Russian preclinical and limited clinical studies, suggests it may help maintain cardiac contractility, reduce fibrosis, and support overall cardiovascular resilience.
0 RCT · 0 human · 0 preclinical
Cardiovascular
Carnosine (beta-alanyl-L-histidine)
Human-limitedNatural anti-glycation and antioxidant dipeptide
Natural dipeptide for anti-glycation & cellular protection.
0 RCT · 0 human · 0 preclinical
longevity
Ceramide Peptide (Hexapeptide-11)
Human-limitedHexapeptide for ceramide synthesis and barrier repair
Ceramide-boosting peptide for skin barrier repair.
0 RCT · 0 human · 0 preclinical
skin
CJC-1295
Human-limitedLong-acting GHRH analog for GH elevation
A long-acting GHRH analog that extends the half-life of endogenous growth hormone releasing hormone, producing sustained elevation of GH and IGF-1.
0 RCT · 0 human · 0 preclinical
growth
CJC-1295 (No DAC) + Ipamorelin 5mg Blend
Human-limitedSynergistic GH pulse amplifier for body and recovery
CJC-1295 (without DAC) + Ipamorelin is a synergistic peptide blend combining a growth hormone-releasing hormone (GHRH) analogue with a selective growth hormone secretagogue. Together, they stimulate the pituitary gland to release growth hormone in a pulsatile, physiologically natural manner. This combination is widely used for body composition improvement, recovery, anti-aging, and sleep quality enhancement.
0 RCT · 0 human · 0 preclinical
growth
CJC-1295 (Without DAC)
Human-limitedNatural GH Pulses for Growth and Recovery
CJC-1295 without DAC (also known as Modified GRF 1-29) is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to release growth hormone in a pulsatile, physiologically natural pattern. It consists of the first 29 amino acids of GHRH with four key amino acid substitutions that enhance stability and receptor affinity compared to the native peptide. It is widely used in research settings for its potential to promote lean muscle growth, fat loss, recovery, and anti-aging effects.
0 RCT · 0 human · 0 preclinical
growth
CJC-1295 with DAC
Human-limitedLong-acting GHRH analog for sustained GH release
CJC-1295 with DAC is a synthetic, long-acting analog of growth hormone-releasing hormone (GHRH) that incorporates a Drug Affinity Complex (DAC) to dramatically extend its half-life. By binding covalently to serum albumin, it maintains sustained elevation of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) for up to two weeks per injection. It is used in research settings to study GH secretion, body composition changes, and recovery processes.
0 RCT · 0 human · 0 preclinical
growth
Collagen peptides (Hydrolyzed Collagen)
Human-limitedHydrolyzed collagen for structural support
Hydrolyzed collagen for skin, joint & bone support.
0 RCT · 0 human · 0 preclinical
skin
Copper Tripeptide-1 (GHK-Cu Injectable)
Human-limitedSystemic copper tripeptide for whole-body rejuvenation
Injectable copper peptide for systemic tissue repair.
0 RCT · 0 human · 0 preclinical
longevity
Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-ake)
Human-limitedSnake venom analog for expression lines
Snake venom-like peptide for dynamic wrinkle relaxation.
0 RCT · 0 human · 0 preclinical
skin
Dulaglutide
Human-limitedLong-acting GLP-1 receptor agonist
Weekly GLP-1 agonist for diabetes & weight management.
0 RCT · 0 human · 0 preclinical
fat-loss
Exenatide
Human-limitedSynthetic exendin-4 GLP-1 agonist
Exendin-4 synthetic peptide for glycemic control.
0 RCT · 0 human · 0 preclinical
fat-loss
GHK-Cu
Human-limitedCellular rejuvenation & collagen synthesis
A naturally occurring copper-binding tripeptide found in human plasma that declines with age, known for its regenerative, anti-inflammatory, and gene-regulatory properties.
0 RCT · 0 human · 0 preclinical
skin
GHK-Cu (Recovery)
Human-limitedCopper tripeptide for recovery and repair
Copper peptide for tissue remodeling & recovery.
0 RCT · 0 human · 0 preclinical
Recovery
GHK-Cu (Topical)
Human-limitedTopical copper peptide for wound repair
Copper tripeptide for accelerated wound healing & scar reduction.
0 RCT · 0 human · 0 preclinical
healing
GHRP-2
Human-limitedPotent GH secretagogue for muscle and recovery
Growth hormone releasing peptide-2 for lean mass & recovery.
0 RCT · 0 human · 0 preclinical
growth
Glutathione
Human-limitedMaster antioxidant for detox and cellular defense
Glutathione is a tripeptide antioxidant composed of glutamate, cysteine, and glycine that is naturally synthesized in virtually every cell of the body. It serves as the body's master antioxidant, neutralizing reactive oxygen species, supporting detoxification pathways, and maintaining redox homeostasis. Declining glutathione levels are associated with aging, chronic disease, and oxidative stress-related conditions.
0 RCT · 0 human · 0 preclinical
Immune
Gonadorelin
Human-limitedGonadotropin-releasing hormone agonist
GnRH analog for fertility and hormonal assessment.
0 RCT · 0 human · 0 preclinical
sexual
Hexapeptide-9 (Vaccinium Myrtillus Peptide)
Human-limitedBilberry-derived peptide for pigmentation
Antioxidant peptide for dark spots and photoaging.
0 RCT · 0 human · 0 preclinical
skin
Hexarelin
Human-limitedPotent growth hormone releasing peptide
Potent GH secretagogue with cardioprotective effects.
0 RCT · 0 human · 0 preclinical
growth
Hexarelin Acetate
Human-limitedPotent GH secretagogue with cardiac benefits
Hexarelin Acetate is a synthetic hexapeptide and potent growth hormone secretagogue (GHS) that stimulates pituitary release of growth hormone (GH) by mimicking the action of ghrelin. It binds to the GHS-R1a receptor with high affinity and also exhibits direct cardioprotective effects independent of GH release. Developed originally as a potential treatment for GH deficiency, it is one of the most potent GH-releasing peptides studied in clinical research.
0 RCT · 0 human · 0 preclinical
growth
HGH Fragment 176-191
Human-limitedTargeted fat-loss fragment of growth hormone
HGH Fragment 176-191 is a synthetic peptide derived from amino acids 176–191 of the C-terminus of human growth hormone (hGH). It was specifically engineered to retain the lipolytic (fat-burning) properties of hGH while eliminating its growth-promoting and insulin-desensitizing effects. Research, primarily in animal models, suggests it stimulates fat breakdown and inhibits the formation of new fat cells.
0 RCT · 0 human · 0 preclinical
fat-loss
Ipamorelin
Human-limitedGH-releasing peptide for lean mass and recovery
A selective growth hormone secretagogue and ghrelin mimetic that stimulates pituitary GH release with high specificity and minimal effect on cortisol or prolactin.
0 RCT · 0 human · 0 preclinical
growth
Kisspeptin-10
Human-limitedEndogenous HPG axis activator for sexual health
Kisspeptin-10 is the biologically active C-terminal decapeptide fragment of the larger kisspeptin precursor protein, encoded by the KISS1 gene. It acts as a potent endogenous activator of the hypothalamic-pituitary-gonadal (HPG) axis, stimulating the release of gonadotropin-releasing hormone (GnRH) and downstream luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It is investigated for applications in reproductive endocrinology, sexual function, and mood regulation.
0 RCT · 0 human · 0 preclinical
sexual
Lactoferrin
Human-limitedIron-binding protein for immunity and gut barrier
Iron-binding glycoprotein for immune & gut health.
0 RCT · 0 human · 0 preclinical
Immune
Leuprolide (Lupron)
Human-limitedLong-acting GnRH agonist for hormone therapy
Long-acting GnRH agonist for hormone suppression.
0 RCT · 0 human · 0 preclinical
sexual
Lipo-C
Human-limitedLipotropic blend for fat loss and liver health
Lipo-C is a lipotropic injection blend combining several compounds—typically methionine, inositol, choline, carnitine, and B vitamins—designed to support fat metabolism and liver function. It promotes the mobilization and breakdown of fat deposits, particularly in the liver. The formulation is commonly used in weight loss programs to enhance lipolysis and improve metabolic efficiency.
0 RCT · 0 human · 0 preclinical
fat-loss
Liraglutide
Human-limitedGLP-1 analog for daily weight management
Short-acting GLP-1 agonist for weight loss & diabetes.
0 RCT · 0 human · 0 preclinical
fat-loss
Lixisenatide
Human-limitedShort-acting GLP-1 for post-meal control
Short-acting GLP-1 agonist for post-meal glucose.
0 RCT · 0 human · 0 preclinical
fat-loss
LL-37
Human-limitedHuman antimicrobial peptide for immunity and healing
LL-37 is a 37-amino acid human host defense peptide derived from the cathelicidin family, naturally produced by neutrophils, epithelial cells, and macrophages. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and viruses while simultaneously modulating immune responses and promoting wound healing. Research suggests it plays a critical role in innate immunity and may have therapeutic applications in chronic infections, wound repair, and inflammatory conditions.
0 RCT · 0 human · 0 preclinical
Immune
Melanotan II
Human-limitedPotent tanning and libido melanocortin agonist
Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) originally developed at the University of Arizona. It potently activates melanocortin receptors to stimulate skin tanning, increase sexual arousal, and suppress appetite. Unlike natural α-MSH, its cyclic structure confers greater receptor affinity and metabolic stability.
0 RCT · 0 human · 0 preclinical
skin
NAD+ (Nicotinamide Riboside)
Human-limitedNAD+ precursor for cellular energy and repair
NAD+ precursor for cellular energy & DNA repair.
0 RCT · 0 human · 0 preclinical
Mitochondrial
Oligopeptide-177 (Blue Peptide)
Human-limitedMarine-derived oligopeptide for moisture
Ocean-derived peptide for hydration and barrier repair.
0 RCT · 0 human · 0 preclinical
skin
Ornithine Alpha-Ketoglutarate (OKG)
Human-limitedDipeptide for nitrogen retention and muscle recovery
Dipeptide precursor for muscle protein synthesis.
0 RCT · 0 human · 0 preclinical
growth
Palmitoyl Pentapeptide-4 (Matrixyl)
Human-limitedPalmitoyl pentapeptide for collagen signaling
Topical signaling peptide for collagen synthesis & anti-wrinkle.
0 RCT · 0 human · 0 preclinical
skin
Palmitoyl Tetrapeptide-7 (Rigin variant)
Human-limitedPalmitoylated tetrapeptide-7 for skin repair
Lipopeptide for collagen repair and anti-inflammation.
0 RCT · 0 human · 0 preclinical
longevity
Palmitoyl Tripeptide-1 (Pal-GHK)
Human-limitedPalmitoyl tripeptide-1 for skin repair
Topical signaling peptide for collagen & wound healing.
0 RCT · 0 human · 0 preclinical
skin
Pentapeptide-18 (Leuphasyl)
Human-limitedLeu-enkephalin analog for expression lines
Topical neuropeptide for gentle muscle relaxation.
0 RCT · 0 human · 0 preclinical
skin
Pentosan Polysulfate (PPS)
Human-limitedPolysulfated xylopyranose for cartilage and interstitial cystitis
Semi-synthetic peptide for osteoarthritis & bladder health.
0 RCT · 0 human · 0 preclinical
joint
PT-141 (Bremelanotide)
Human-limitedMelanocortin receptor agonist for sexual function
Melanocortin agonist for sexual health & libido.
0 RCT · 0 human · 0 preclinical
sexual
PTH (1-34) Teriparatide
Human-limitedParathyroid hormone analog for bone building
Parathyroid hormone analog for severe osteoporosis anabolic therapy.
0 RCT · 0 human · 0 preclinical
Bone
Selank
Human-limitedAnxiolytic peptide for calm focus and immune support
A synthetic heptapeptide derived from the immunomodulatory peptide tuftsin, developed in Russia for anxiolytic and nootropic effects without the sedation or dependence of benzodiazepines.
0 RCT · 0 human · 0 preclinical
cognition
Semaglutide (Liver Health)
Human-limitedGLP-1 agonist for non-alcoholic fatty liver disease
GLP-1 agonist for fatty liver & metabolic health.
0 RCT · 0 human · 0 preclinical
liver
Snap-8
Human-limitedPeptide wrinkle relaxer targeting neuromuscular signaling
Snap-8 is a synthetic octapeptide cosmetic active designed to reduce the appearance of expression lines and wrinkles by modulating neuromuscular signaling at the dermal-muscle interface. It is an extended analog of Argireline (Acetyl Hexapeptide-3) with two additional amino acids, offering purportedly enhanced efficacy. Originally developed for topical cosmetic application, it has also been explored in research-grade injectable formulations for more direct tissue delivery.
0 RCT · 0 human · 0 preclinical
skin
Tesamorelin
Human-limitedFDA-approved GHRH analog for fat reduction
GHRH analog for visceral fat reduction & GH elevation.
0 RCT · 0 human · 0 preclinical
fat-loss
Tetrapeptide-30 (Skin Tightener)
Human-limitedTetrapeptide for immediate and lasting firming
Instant tightening & long-term lifting peptide.
0 RCT · 0 human · 0 preclinical
skin
Tetrapeptide-7 (Rigin)
Human-limitedTetrapeptide-7 for extracellular matrix repair
Anti-inflammatory peptide for skin rejuvenation.
0 RCT · 0 human · 0 preclinical
longevity
Thymalin/Thymulin
Human-limitedThymic peptide restoring immune vitality with age
Thymalin is a thymic peptide preparation derived from calf thymus glands, while Thymulin (FTS) is a naturally occurring nonapeptide produced by thymic epithelial cells that requires zinc as a cofactor for biological activity. Together they represent thymic-origin immunomodulatory compounds that restore and regulate T-lymphocyte differentiation, maturation, and function. They are used primarily to support immune system integrity, combat immunosenescence, and may have applications in anti-aging and recovery protocols.
0 RCT · 0 human · 0 preclinical
Immune
Thymosin Alpha-1
Human-limitedThymus peptide for lung immune defense
Thymus peptide for immune modulation & respiratory health.
0 RCT · 0 human · 0 preclinical
Respiratory
Thymosin Alpha-1
Human-limitedThymus peptide for immune system enhancement
Immune modulator for T-cell enhancement & infection support.
0 RCT · 0 human · 0 preclinical
Immune
Tirzepatide
Human-limitedDual GIP/GLP-1 receptor agonist
Dual GIP/GLP-1 agonist for superior weight loss & glycemic control.
0 RCT · 0 human · 0 preclinical
fat-loss
Tripeptide-1 (Growth Factor Fragment)
Human-limitedGrowth factor mimetic for skin and hair
Growth factor mimetic for skin rejuvenation.
0 RCT · 0 human · 0 preclinical
skin
Acetyl Tetrapeptide-3 (Darnosine)
AnimalAcetyl tetrapeptide-3 for AGE prevention
Advanced AGE-breaker for deep anti-wrinkle action.
0 RCT · 0 human · 0 preclinical
longevity
Adipotide (FTTP)
AnimalTargeted fat-depot destruction via vascular apoptosis
Adipotide (also called FTTP) is an experimental peptidomimetic compound designed to selectively destroy the blood supply to white adipose tissue by targeting prohibitin, a protein highly expressed on the vasculature feeding fat cells. Originally developed at MD Anderson Cancer Center, it demonstrated dramatic fat loss in obese rhesus monkeys without dietary restriction. It remains a research compound with no approved human clinical use.
0 RCT · 0 human · 0 preclinical
fat-loss
ARA-290 (Cibinetide)
AnimalErythropoietin analog for kidney protection
Erythropoietin-derived peptide for kidney & nerve protection.
0 RCT · 0 human · 0 preclinical
kidney
B7-33
AnimalBiased RXFP1 agonist for cardiac fibrosis
B7-33 is a single-chain peptide analog of human relaxin-2, engineered to selectively activate the RXFP1 receptor without triggering the cAMP signaling pathway. It demonstrates potent anti-fibrotic, vasodilatory, and cardioprotective effects in preclinical models. Research primarily focuses on its potential in heart failure, pulmonary arterial hypertension, and organ fibrosis.
0 RCT · 0 human · 0 preclinical
Cardiovascular
BPC-157
AnimalSystemic healing for wounds, tendons, and gut
A synthetic pentadecapeptide derived from a protein in gastric juice, studied for tissue repair, gut protection, and musculoskeletal healing.
0 RCT · 0 human · 0 preclinical
healing
BPC-157 (Liver)
AnimalPentadecapeptide for liver protection
Body protection compound for liver detoxification & repair.
0 RCT · 0 human · 0 preclinical
liver
BPC-157 + TB-500 Blend (10mg + 10mg)
AnimalSynergistic healing and recovery peptide blend
BPC-157 + TB-500 is a pre-mixed peptide blend combining Body Protection Compound-157 (a gastric pentadecapeptide) and Thymosin Beta-4 fragment (TB-500) into a single vial for convenience. Together, these two peptides target overlapping and complementary pathways in tissue repair, angiogenesis, and inflammation modulation. The combination is widely used in the research and biohacking communities for accelerated musculoskeletal recovery, tendon and ligament healing, and systemic anti-inflammatory effects.
0 RCT · 0 human · 0 preclinical
Recovery
BPC-157 + TB-500 Blend (5mg + 5mg)
AnimalSynergistic repair blend for accelerated healing
BPC-157 + TB-500 is a synergistic peptide blend combining Body Protection Compound-157 (5mg) and Thymosin Beta-4 fragment TB-500 (5mg) into a single vial. BPC-157 is a synthetic pentadecapeptide derived from a protective gastric protein, while TB-500 is a synthetic analog of the actin-sequestering protein Thymosin Beta-4, both of which promote tissue repair and regeneration. Together, they are widely used in research for accelerated healing of musculoskeletal injuries, tendons, ligaments, and soft tissue damage.
0 RCT · 0 human · 0 preclinical
Recovery
Calcitonin (Salmon)
AnimalSalmon calcitonin for bone density
Calcium-regulating peptide for bone density & fracture prevention.
0 RCT · 0 human · 0 preclinical
Bone
Cerebrolysin
AnimalNeurotrophic peptide blend for cognitive repair
Neurotrophic peptide mix for brain repair & cognitive recovery.
0 RCT · 0 human · 0 preclinical
cognition
Cortagen
AnimalPineal-derived peptide for brain and immunity
Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Pro) derived from the pineal gland and developed within the Russian peptide bioregulator program. It is primarily studied for its neuroprotective and immunomodulatory properties, with research suggesting it may support cortical function, slow age-related neurological decline, and modulate immune responses. Most of its evidence base comes from Russian preclinical and limited clinical studies conducted in the 1980s–2000s.
0 RCT · 0 human · 0 preclinical
cognition
Crystagen
AnimalOcular cytoprotection via crystallin chaperone mimicry
Crystagen is a synthetic peptide derived from the alpha-crystallin protein family, small heat-shock proteins (sHSPs) naturally abundant in the eye lens. It is investigated primarily for its cytoprotective and anti-apoptotic properties in ocular tissues, with emerging research suggesting neuroprotective and anti-inflammatory effects. Evidence is largely limited to animal and in vitro models, and no approved clinical use currently exists.
0 RCT · 0 human · 0 preclinical
eye
Decapeptide-12 (Melanostatine-5)
AnimalDecapeptide for melanin reduction
Melanin-inhibiting peptide for hyperpigmentation.
0 RCT · 0 human · 0 preclinical
skin
Dermorphin
AnimalUltra-potent frog-derived mu-opioid peptide
Dermorphin is a naturally occurring heptapeptide opioid first isolated from the skin secretions of South American phyllomedusa frogs. It binds with extraordinarily high selectivity and affinity to mu-opioid receptors, producing potent analgesic and sedative effects estimated to be 30–40 times more potent than morphine on a molar basis. Its unique structure incorporates a D-amino acid (D-Ala), which confers resistance to enzymatic degradation and prolongs its biological activity.
0 RCT · 0 human · 0 preclinical
mood
Dermorphin
AnimalPotent frog-derived mu-opioid receptor agonist
Dermorphin is a naturally occurring heptapeptide opioid first isolated from the skin of South American Phyllomedusa frogs. It binds with extraordinarily high selectivity and potency to mu-opioid receptors, producing analgesic effects estimated to be 30–40 times more potent than morphine on a molar basis. Research has primarily been conducted in animal models, with extremely limited controlled human data available.
0 RCT · 0 human · 0 preclinical
mood
DSIP (Delta Sleep-Inducing Peptide)
AnimalDelta sleep-inducing peptide for deep sleep
Natural peptide for deep sleep induction & stress reduction.
0 RCT · 0 human · 0 preclinical
sleep
Epitalon
AnimalPineal tetrapeptide for sleep and rhythm
A synthetic tetrapeptide derived from Epithalamin (a pineal gland extract) that has been studied for telomere elongation, circadian rhythm normalization, and lifespan extension in animal models.
0 RCT · 0 human · 0 preclinical
longevity
Epithalon
AnimalExtend your cellular lifespan
A synthetic tetrapeptide that activates telomerase — the enzyme that protects your chromosomes from aging.
0 RCT · 0 human · 0 preclinical
longevity
FOXO4-DRI
AnimalSenolytic peptide targeting cellular senescence
FOXO4-DRI is a D-amino acid retro-inverso peptide designed to selectively induce apoptosis in senescent cells by disrupting the interaction between FOXO4 and p53. It belongs to a class of experimental senolytic compounds—agents that clear aged, dysfunctional 'zombie' cells from tissues. Research has been conducted primarily in mouse models, where it demonstrated improvements in fitness, fur density, kidney function, and lifespan metrics.
0 RCT · 0 human · 0 preclinical
longevity
FST 344
AnimalMyostatin blocker for serious muscle hypertrophy
FST 344 is a recombinant isoform of follistatin, a naturally occurring glycoprotein that binds and neutralizes myostatin and activin, two potent inhibitors of muscle growth. By suppressing these negative regulators, FST 344 promotes skeletal muscle hypertrophy, enhances recovery, and may support bone density. It has been investigated in gene therapy and preclinical contexts for muscular dystrophy and sarcopenia, though human clinical data remain very limited.
0 RCT · 0 human · 0 preclinical
growth
FTPP Adipotide
AnimalTargeted fat-depot elimination via vascular apoptosis
Adipotide is a pro-apoptotic peptidomimetic designed to selectively destroy the blood supply feeding white adipose tissue (WAT), causing fat cell death through targeted vascular disruption. It was developed at MD Anderson Cancer Center primarily as an anti-obesity compound and has shown dramatic fat loss in non-human primate studies. Human clinical data remains extremely limited, and it is considered a research compound only.
0 RCT · 0 human · 0 preclinical
fat-loss
GDF-8 (Myostatin)
AnimalThe Master Brake on Muscle Growth
GDF-8, also known as myostatin, is a TGF-β superfamily member that acts as a potent negative regulator of skeletal muscle mass. It limits muscle fiber size and number by inhibiting myoblast proliferation and differentiation. Research into myostatin inhibition has generated significant interest for applications in muscle wasting diseases, metabolic disorders, and athletic performance.
0 RCT · 0 human · 0 preclinical
growth
GHRP-3
AnimalThird-generation GH secretagogue with refined selectivity
GHRP-3 is a synthetic hexapeptide and member of the growth hormone releasing peptide family, designed to stimulate the pulsatile release of growth hormone (GH) from the anterior pituitary gland. It acts primarily as a ghrelin mimetic and GHS-R1a agonist, amplifying natural GH secretion pulses. GHRP-3 is structurally related to GHRP-2 and GHRP-6 but exhibits a modified amino acid sequence intended to reduce appetite-stimulating side effects while maintaining GH secretagogue potency.
0 RCT · 0 human · 0 preclinical
growth
GHRP-6
AnimalGH-releasing peptide with orexigenic effects
Growth hormone releasing peptide with appetite stimulation.
0 RCT · 0 human · 0 preclinical
growth
GLOW (BPC-157 + GHK-Cu + TB-500 Blend)
AnimalRegenerate, Renew, Glow From Within
GLOW is a synergistic peptide blend combining BPC-157 (10mg), GHK-Cu (50mg), and TB-500 (10mg) into a single formulation designed to accelerate tissue repair, promote skin rejuvenation, and support systemic recovery. BPC-157 and TB-500 target musculoskeletal and gut healing, while GHK-Cu drives collagen synthesis, anti-inflammatory signaling, and skin remodeling. Together, these three peptides work across complementary pathways to produce enhanced regenerative and cosmetic outcomes.
0 RCT · 0 human · 0 preclinical
healing
GLP-1 (7-36) Amide
AnimalEndogenous GLP-1 for meal-time satiety
Native GLP-1 peptide for acute appetite control.
0 RCT · 0 human · 0 preclinical
fat-loss
IGF-1 LR3
AnimalLong-R3 insulin-like growth factor for muscle differentiation
Long-acting IGF-1 analog for muscle growth & differentiation.
0 RCT · 0 human · 0 preclinical
growth
KPV
AnimalTripeptide for intestinal inflammation reduction
Alpha-MSH fragment for gut-specific anti-inflammatory effects.
0 RCT · 0 human · 0 preclinical
gut
Mechano Growth Factor (MGF)
AnimalLocal muscle repair signal for accelerated recovery
Mechano Growth Factor (MGF) is a splice variant of Insulin-like Growth Factor 1 (IGF-1) that is produced locally in muscle and other tissues in response to mechanical stress or damage. It plays a critical role in activating satellite cells (muscle stem cells) to initiate repair and hypertrophy. MGF is primarily of interest to researchers studying muscle regeneration, athletic recovery, and tissue repair.
0 RCT · 0 human · 0 preclinical
growth
Melanotan I (Melanotan-1)
AnimalSelective melanocortin-1 receptor agonist
Selective MC1-R agonist for UV-free tanning.
0 RCT · 0 human · 0 preclinical
skin
Melanotan II
AnimalMelanocortin agonist for tanning and sexual function
Melanocortin peptide for tanning & libido enhancement.
0 RCT · 0 human · 0 preclinical
skin
Myristoyl Pentapeptide-17 (Keratinocyte Growth Factor Fragment)
AnimalMyristoyl pentapeptide for hair stimulation
Keratinocyte-stimulating peptide for hair growth.
0 RCT · 0 human · 0 preclinical
skin
Oligopeptide-68 (Progeline)
AnimalOligopeptide-68 for cellular aging reversal
Anti-senescence peptide that reduces progerin.
0 RCT · 0 human · 0 preclinical
longevity
Orexin B
AnimalWakefulness neuropeptide driving arousal and cognition
Orexin B (also known as Hypocretin-2) is a neuropeptide produced in the lateral hypothalamus that plays a central role in regulating wakefulness, arousal, appetite, and energy homeostasis. It acts primarily through the OX2 receptor (orexin receptor type 2) to promote and maintain wakefulness and modulate feeding behavior. Research into orexin B is largely preclinical, but it has significant implications for understanding narcolepsy, sleep disorders, and metabolic regulation.
0 RCT · 0 human · 0 preclinical
sleep
PE-22-28
AnimalNovel TREK-1 inhibitor for mood and cognition
PE-22-28 is a synthetic peptide analog derived from the propeptide of neurotensin (also related to the TREK-1 channel inhibitor spadin), engineered to inhibit TREK-1 potassium channels in the brain. It has demonstrated rapid antidepressant-like effects in preclinical rodent models, often acting faster than conventional antidepressants. Research interest is growing due to its novel mechanism and potential to address treatment-resistant depression.
0 RCT · 0 human · 0 preclinical
mood
Pentadecapeptide BPC-157 (Oral Stable)
AnimalOral-stable pentadecapeptide for GI repair
Gut-stable oral BPC-157 for digestive healing.
0 RCT · 0 human · 0 preclinical
gut
Peptide YY (PYY 3-36)
AnimalEndogenous Y2 receptor agonist for satiety
Natural appetite-suppressing gut peptide.
0 RCT · 0 human · 0 preclinical
fat-loss
Pinealon
AnimalPineal tripeptide for better sleep
Pineal peptide for circadian rhythm & sleep quality improvement.
0 RCT · 0 human · 0 preclinical
sleep
PNC-27
AnimalSelective cancer cell membrane-targeting peptide
PNC-27 is a synthetic peptide derived from the p53 tumor suppressor protein, designed to selectively induce apoptosis in cancer cells while leaving normal cells unharmed. It contains an MDM-2-binding domain of p53 fused to a transmembrane-penetrating sequence, enabling it to insert into the membranes of cancer cells that aberrantly express HDM-2 on their surface. Research has been conducted primarily in vitro and in animal models, with very limited human data available.
0 RCT · 0 human · 0 preclinical
Immune
Semax
AnimalNootropic ACTH analog for cognitive enhancement
Nootropic peptide for memory, focus & neuroprotection.
0 RCT · 0 human · 0 preclinical
cognition
SLU-PP-322
AnimalExercise mimetic targeting mitochondrial energy pathways
SLU-PP-322 is a synthetic small-molecule agonist of estrogen-related receptors (ERRα, ERRβ, and ERRγ) developed at Saint Louis University. It mimics the metabolic effects of sustained aerobic exercise at the cellular level, promoting mitochondrial biogenesis, fatty acid oxidation, and endurance capacity without physical activity. In preclinical animal studies, it has demonstrated significant improvements in exercise performance, fat metabolism, and cardiac function.
0 RCT · 0 human · 0 preclinical
Mitochondrial
SS-31 (Elamipretide)
AnimalMitochondrial peptide for renal protection
Mitochondrial-targeted peptide for kidney & metabolic protection.
0 RCT · 0 human · 0 preclinical
kidney
SS-31 (Elamipretide)
AnimalMitochondrial peptide for metabolic and renal health
Mitochondrial-targeted peptide for metabolic & kidney protection.
0 RCT · 0 human · 0 preclinical
metabolic
TB-500
AnimalThymosin beta-4 fragment for wound repair
A synthetic fragment of Thymosin Beta-4, a naturally occurring protein involved in actin regulation, tissue repair, and inflammation modulation.
0 RCT · 0 human · 0 preclinical
healing
TB-500
AnimalAccelerate healing, reduce inflammation, restore mobility
TB-500 is a synthetic peptide fragment derived from Thymosin Beta-4, a naturally occurring protein found in virtually all human and animal cells. It promotes tissue repair, reduces inflammation, and accelerates healing of muscles, tendons, ligaments, and skin. It is widely used in research and sports recovery contexts for its potent regenerative properties.
0 RCT · 0 human · 0 preclinical
Recovery
TB-500 (Recovery)
AnimalThymosin beta-4 for injury recovery
Thymosin beta-4 for systemic recovery & inflammation reduction.
0 RCT · 0 human · 0 preclinical
Recovery
Tetrapeptide-21 (Ganirelix analog)
AnimalTetrapeptide for hair follicle activation
Hair growth peptide for follicle stimulation.
0 RCT · 0 human · 0 preclinical
skin
Tetrapeptide-68 (Adifyline)
AnimalTetrapeptide for facial fat restoration
Adipogenesis peptide for facial volume restoration.
0 RCT · 0 human · 0 preclinical
skin
Thymulin
AnimalThymus peptide for respiratory immune balance
Thymus peptide for immune balance & lung protection.
0 RCT · 0 human · 0 preclinical
Respiratory
Thymulin
AnimalThymus peptide for immune modulation
Thymus peptide for immune balance & T-cell maturation.
0 RCT · 0 human · 0 preclinical
Immune
Vasopressin (ADH analog)
AnimalAntidiuretic hormone peptide
Antidiuretic hormone for water retention & blood pressure.
0 RCT · 0 human · 0 preclinical
Cardiovascular
Vilon
AnimalThymus dipeptide for immune and DNA health
Thymus dipeptide for immune restoration & DNA repair.
0 RCT · 0 human · 0 preclinical
Immune
VIP (Vasoactive Intestinal Peptide)
AnimalVasoactive intestinal peptide for ocular health
Neuroprotective peptide for dry eye & retinal health.
0 RCT · 0 human · 0 preclinical
eye
Ziconotide (MVIIA ω-conotoxin)
AnimalConotoxin analog for intractable pain
Conopeptide for severe intrathecal pain management.
0 RCT · 0 human · 0 preclinical
cognition
ACE-031
AnecdotalACVR2B-Fc myostatin/activin trap
ACVR2B-Fc fusion protein for myostatin & activin inhibition.
0 RCT · 0 human · 0 preclinical
growth
Adamax
AnecdotalNootropic peptide blend for cognition and mood
Adamax is a research peptide blend reported to combine nootropic and neuroprotective peptide components aimed at enhancing cognitive function, mood stability, and neural recovery. It is marketed primarily for its potential effects on dopaminergic and serotonergic signaling pathways. Evidence is largely limited to preclinical and anecdotal sources, with no published human clinical trials specific to the Adamax formulation.
0 RCT · 0 human · 0 preclinical
cognition
AOD-9604
AnecdotalHGH fragment for lipolysis stimulation
HGH fragment for localized fat metabolism.
0 RCT · 0 human · 0 preclinical
fat-loss
DauD2 (Defensin-like peptide)
AnecdotalAntimicrobial defensin-like peptide
Antimicrobial & immune peptide for acne and infection.
0 RCT · 0 human · 0 preclinical
skin
Davunetide (AL-108)
AnecdotalNAPVSIPQ peptide for microtubule stabilization
Neuroprotective peptide for tauopathies (Alzheimer's, PSP).
0 RCT · 0 human · 0 preclinical
cognition
Dihexa
AnecdotalHepatocyte growth factor agonist for neurogenesis
Potent neurogenic peptide for cognitive repair.
0 RCT · 0 human · 0 preclinical
cognition
Follistatin-344
AnecdotalMyostatin antagonist for muscle hyperplasia
Myostatin inhibitor for extreme muscle growth.
0 RCT · 0 human · 0 preclinical
growth
FOXO4-DRI
AnecdotalSenolytic peptide for cellular rejuvenation
Senolytic peptide that clears aged & damaged cells.
0 RCT · 0 human · 0 preclinical
longevity
Frag 17-23
AnecdotalExperimental GH fragment targeting fat metabolism
Frag 17-23 is a short synthetic peptide fragment derived from amino acids 17 through 23 of the human growth hormone (hGH) sequence. It is hypothesized to retain lipolytic properties similar to larger hGH fragments while being structurally distinct from the more widely studied Frag 176-191. Evidence for its efficacy in humans remains largely anecdotal, with minimal published research specific to this fragment.
0 RCT · 0 human · 0 preclinical
fat-loss
GHRP-4
AnecdotalPituitary GH secretagogue for growth and recovery
GHRP-4 is a synthetic hexapeptide ghrelin mimetic designed to stimulate the pituitary gland's release of endogenous growth hormone. It belongs to the same family as GHRP-2 and GHRP-6 but is a less extensively characterized analog with a modified structure aimed at optimizing GH release with a potentially reduced appetite-stimulating side effect profile. Research on GHRP-4 specifically is limited compared to its better-studied relatives, and most mechanistic understanding is extrapolated from the broader GHRP class.
0 RCT · 0 human · 0 preclinical
growth
Humanin
AnecdotalMitochondrial peptide for brain protection
Mitochondrial-derived neuroprotective peptide.
0 RCT · 0 human · 0 preclinical
cognition
KLOW
AnecdotalElectrolyte balance and cardiovascular metabolic support
KLOW is a research compound or proprietary peptide blend purported to support electrolyte balance, cardiovascular function, and cellular metabolic homeostasis. It is marketed within the peptide research space, though its precise composition and mechanism are not well-established in peer-reviewed literature. Evidence for its specific effects remains largely anecdotal and preclinical.
0 RCT · 0 human · 0 preclinical
metabolic
KPV-cyclo (cyclo-KPV)
AnecdotalCyclized KPV for IBD and gut inflammation
Cyclized KPV analog for enhanced gut stability.
0 RCT · 0 human · 0 preclinical
gut
LL-37
AnecdotalAntimicrobial peptide for respiratory defense
Cathelicidin antimicrobial peptide for lung infection clearance.
0 RCT · 0 human · 0 preclinical
Respiratory
LL-37
AnecdotalCathelicidin peptide for innate immunity
Cathelicidin-derived antimicrobial & immune-modulating peptide.
0 RCT · 0 human · 0 preclinical
Immune
MOTS-c
AnecdotalMitochondrial-encoded peptide for glucose control
Mitochondrial-derived peptide for metabolic regulation & insulin sensitivity.
0 RCT · 0 human · 0 preclinical
metabolic
NAPVSIPQ (ADNP fragment)
AnecdotalActive fragment of neuroprotective protein ADNP
Activity-dependent neuroprotective peptide fragment.
0 RCT · 0 human · 0 preclinical
cognition
PEG-MGF
AnecdotalPEG-MGF for muscle hyperplasia and repair
PEGylated Mechano Growth Factor for muscle stem cell activation.
0 RCT · 0 human · 0 preclinical
growth
TGF-β1 Mimetic Peptide (Tetrapeptide-28)
AnecdotalTetrapeptide-28 for scarless healing
TGF-β1 mimicking peptide for scar reduction.
0 RCT · 0 human · 0 preclinical
healing
Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.