Overview
Positively charged peptide binds to negatively charged bacterial membranes, forming pores and causing osmotic lysis.
Proposed mechanism
DauD2 is a synthetic defensin mimetic that disrupts bacterial cell membranes via electrostatic interaction, similar to natural host defense peptides.
What the evidence supports
Evidence rests primarily on self-reported experience. Controlled studies are lacking.
Graded Anecdotal
Case reports, clinician notes, and user-reported outcomes. Recorded for completeness and labelled plainly so it is never mistaken for data.
Key citations
Representative primary sources, including results that did not favour the compound.
- [1]
Defensin peptides in acne
· DOI:10.1111/ics.12543 · 2019
- [2]
Antimicrobial peptides
· DOI:10.1038/nrd3031 · 2010
- [3]
Defensin peptides in acne (2019)
· · 0
- [4]
Antimicrobial peptides (2010)
· · 0
Citation records in this build are illustrative placeholders for the design.
Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.