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The library

149 compounds. Every one graded.

Filter by research area or by how strong the evidence actually is. Profiles graded Animal or Anecdotal are not hidden they are labelled, which is more useful.

Clinical
15
Human-limited
61
Animal
54
Anecdotal
19

27 of 149 profiles

Skin & Beauty

Melanotan I

Clinical

Clinical-grade melanocyte activator for photoprotection

Melanotan I (afamelanotide) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that potently stimulates melanogenesis, increasing skin pigmentation without requiring UV exposure. It was developed primarily to protect individuals with photosensitive conditions such as erythropoietic protoporphyria (EPP) from painful phototoxic reactions. Beyond tanning, it has demonstrated anti-inflammatory, photoprotective, and potentially immunomodulatory effects in clinical and preclinical studies.

0 RCT · 0 human · 0 preclinical

skin

Acetyl Hexapeptide-3 (Argireline)

Human-limited

Acetyl hexapeptide for expression lines

Topical neuropeptide for dynamic wrinkle reduction.

0 RCT · 0 human · 0 preclinical

skin

Acetyl Tetrapeptide-5 (Eyeseryl)

Human-limited

Acetyl tetrapeptide-5 for eye area

Under-eye peptide for puffiness reduction.

0 RCT · 0 human · 0 preclinical

skin

AHK-Cu

Human-limited

Copper peptide for skin regeneration and repair

AHK-Cu is a copper-binding tripeptide (Ala-His-Lys) complexed with copper(II) ions, closely related to the well-studied GHK-Cu peptide. It stimulates collagen and glycosaminoglycan synthesis in skin fibroblasts while exerting antioxidant and anti-inflammatory activity. Primarily researched in the context of skin regeneration, wound healing, and hair follicle stimulation.

0 RCT · 0 human · 0 preclinical

skin

Biopeptide CL (Palmitoyl Oligopeptide)

Human-limited

Palmitoyl oligopeptide for collagen synthesis

Collagen-boosting peptide for firming and lifting.

0 RCT · 0 human · 0 preclinical

skin

Ceramide Peptide (Hexapeptide-11)

Human-limited

Hexapeptide for ceramide synthesis and barrier repair

Ceramide-boosting peptide for skin barrier repair.

0 RCT · 0 human · 0 preclinical

skin

Collagen peptides (Hydrolyzed Collagen)

Human-limited

Hydrolyzed collagen for structural support

Hydrolyzed collagen for skin, joint & bone support.

0 RCT · 0 human · 0 preclinical

skin

Dipeptide Diaminobutyroyl Benzylamide Diacetate (Syn-ake)

Human-limited

Snake venom analog for expression lines

Snake venom-like peptide for dynamic wrinkle relaxation.

0 RCT · 0 human · 0 preclinical

skin

GHK-Cu

Human-limited

Cellular rejuvenation & collagen synthesis

A naturally occurring copper-binding tripeptide found in human plasma that declines with age, known for its regenerative, anti-inflammatory, and gene-regulatory properties.

0 RCT · 0 human · 0 preclinical

skin

Hexapeptide-9 (Vaccinium Myrtillus Peptide)

Human-limited

Bilberry-derived peptide for pigmentation

Antioxidant peptide for dark spots and photoaging.

0 RCT · 0 human · 0 preclinical

skin

LL-37

Human-limited

Human antimicrobial peptide for immunity and healing

LL-37 is a 37-amino acid human host defense peptide derived from the cathelicidin family, naturally produced by neutrophils, epithelial cells, and macrophages. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and viruses while simultaneously modulating immune responses and promoting wound healing. Research suggests it plays a critical role in innate immunity and may have therapeutic applications in chronic infections, wound repair, and inflammatory conditions.

0 RCT · 0 human · 0 preclinical

Immune

Melanotan II

Human-limited

Potent tanning and libido melanocortin agonist

Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) originally developed at the University of Arizona. It potently activates melanocortin receptors to stimulate skin tanning, increase sexual arousal, and suppress appetite. Unlike natural α-MSH, its cyclic structure confers greater receptor affinity and metabolic stability.

0 RCT · 0 human · 0 preclinical

skin

Oligopeptide-177 (Blue Peptide)

Human-limited

Marine-derived oligopeptide for moisture

Ocean-derived peptide for hydration and barrier repair.

0 RCT · 0 human · 0 preclinical

skin

Palmitoyl Pentapeptide-4 (Matrixyl)

Human-limited

Palmitoyl pentapeptide for collagen signaling

Topical signaling peptide for collagen synthesis & anti-wrinkle.

0 RCT · 0 human · 0 preclinical

skin

Palmitoyl Tripeptide-1 (Pal-GHK)

Human-limited

Palmitoyl tripeptide-1 for skin repair

Topical signaling peptide for collagen & wound healing.

0 RCT · 0 human · 0 preclinical

skin

Pentapeptide-18 (Leuphasyl)

Human-limited

Leu-enkephalin analog for expression lines

Topical neuropeptide for gentle muscle relaxation.

0 RCT · 0 human · 0 preclinical

skin

Snap-8

Human-limited

Peptide wrinkle relaxer targeting neuromuscular signaling

Snap-8 is a synthetic octapeptide cosmetic active designed to reduce the appearance of expression lines and wrinkles by modulating neuromuscular signaling at the dermal-muscle interface. It is an extended analog of Argireline (Acetyl Hexapeptide-3) with two additional amino acids, offering purportedly enhanced efficacy. Originally developed for topical cosmetic application, it has also been explored in research-grade injectable formulations for more direct tissue delivery.

0 RCT · 0 human · 0 preclinical

skin

Tetrapeptide-30 (Skin Tightener)

Human-limited

Tetrapeptide for immediate and lasting firming

Instant tightening & long-term lifting peptide.

0 RCT · 0 human · 0 preclinical

skin

Tripeptide-1 (Growth Factor Fragment)

Human-limited

Growth factor mimetic for skin and hair

Growth factor mimetic for skin rejuvenation.

0 RCT · 0 human · 0 preclinical

skin

Decapeptide-12 (Melanostatine-5)

Animal

Decapeptide for melanin reduction

Melanin-inhibiting peptide for hyperpigmentation.

0 RCT · 0 human · 0 preclinical

skin

GLOW (BPC-157 + GHK-Cu + TB-500 Blend)

Animal

Regenerate, Renew, Glow From Within

GLOW is a synergistic peptide blend combining BPC-157 (10mg), GHK-Cu (50mg), and TB-500 (10mg) into a single formulation designed to accelerate tissue repair, promote skin rejuvenation, and support systemic recovery. BPC-157 and TB-500 target musculoskeletal and gut healing, while GHK-Cu drives collagen synthesis, anti-inflammatory signaling, and skin remodeling. Together, these three peptides work across complementary pathways to produce enhanced regenerative and cosmetic outcomes.

0 RCT · 0 human · 0 preclinical

healing

Melanotan I (Melanotan-1)

Animal

Selective melanocortin-1 receptor agonist

Selective MC1-R agonist for UV-free tanning.

0 RCT · 0 human · 0 preclinical

skin

Melanotan II

Animal

Melanocortin agonist for tanning and sexual function

Melanocortin peptide for tanning & libido enhancement.

0 RCT · 0 human · 0 preclinical

skin

Myristoyl Pentapeptide-17 (Keratinocyte Growth Factor Fragment)

Animal

Myristoyl pentapeptide for hair stimulation

Keratinocyte-stimulating peptide for hair growth.

0 RCT · 0 human · 0 preclinical

skin

Tetrapeptide-21 (Ganirelix analog)

Animal

Tetrapeptide for hair follicle activation

Hair growth peptide for follicle stimulation.

0 RCT · 0 human · 0 preclinical

skin

Tetrapeptide-68 (Adifyline)

Animal

Tetrapeptide for facial fat restoration

Adipogenesis peptide for facial volume restoration.

0 RCT · 0 human · 0 preclinical

skin

DauD2 (Defensin-like peptide)

Anecdotal

Antimicrobial defensin-like peptide

Antimicrobial & immune peptide for acne and infection.

0 RCT · 0 human · 0 preclinical

skin

Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.