Overview
Activates FGF receptors on hair follicle keratinocytes, promoting proliferation and delaying catagen transition.
Proposed mechanism
Myristoyl pentapeptide-17 is a fragment of keratinocyte growth factor (KGF) that binds to FGFR2 receptors on keratinocytes and dermal papilla cells.
What the evidence supports
Most data comes from preclinical animal studies. Human clinical trial evidence is limited or absent.
Graded Animal
Evidence drawn from in vivo animal models or in vitro systems. Mechanistically informative; translation to humans is unproven.
Key citations
Representative primary sources, including results that did not favour the compound.
- [1]
KGF peptide in hair
· DOI:10.1111/j.1346-8138.2012.01603.x · 2012
- [2]
Peptide hair growth review
· DOI:10.1111/jocd.13287 · 2020
- [3]
KGF peptide in hair (2012)
· · 0
- [4]
Peptide hair growth review (2020)
· · 0
Citation records in this build are illustrative placeholders for the design.
Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.