Overview
Competitively binds to nACh receptors, reducing acetylcholine's ability to trigger muscle contraction.
Proposed mechanism
Syn-ake is a synthetic tripeptide that mimics Waglerin-1 (from snake venom), blocking nicotinic acetylcholine receptors at neuromuscular junctions.
What the evidence supports
Human data exists but the trials are small, short-term, or not yet replicated.
Graded Human-limited
Human data that exists but is thin: open-label work, single-arm studies, small cohorts, or observational follow-up without randomisation.
Key citations
Representative primary sources, including results that did not favour the compound.
- [1]
Syn-ake clinical study
· DOI:10.1111/j.1473-2165.2006.00233.x · 2006
- [2]
Neuropeptide cosmetics
· DOI:10.1111/jocd.12404 · 2017
- [3]
Syn-ake clinical study (2006)
· · 0
- [4]
Neuropeptide cosmetics (2017)
· · 0
Citation records in this build are illustrative placeholders for the design.
Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.