Overview
Interacts with pinealocytes to optimize melatonin production and circadian gene expression.
Proposed mechanism
Pinealon is a synthetic tripeptide that regulates pineal function, influences melatonin synthesis, and protects against oxidative damage in brain tissue.
What the evidence supports
Most data comes from preclinical animal studies. Human clinical trial evidence is limited or absent.
Graded Animal
Evidence drawn from in vivo animal models or in vitro systems. Mechanistically informative; translation to humans is unproven.
Key citations
Representative primary sources, including results that did not favour the compound.
- [1]
Pineal peptides and aging
· DOI:10.1016/j.neulet.2008.06.003 · 2008
- [2]
Peptide regulation of pineal
· DOI:10.1134/S0006297910020100 · 2010
- [3]
Pineal peptides and aging (2008)
· · 0
- [4]
Peptide regulation of pineal (2010)
· · 0
Citation records in this build are illustrative placeholders for the design.
Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.