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AnimalSalmon calcitonin for bone density

Calcitonin (Salmon)

Calcium-regulating peptide for bone density & fracture prevention.

Overview

Binds to calcitonin receptors on osteoclasts, decreasing their activity and reducing calcium release into blood.

Proposed mechanism

Salmon calcitonin binds to calcitonin receptors on osteoclasts, inhibiting bone resorption and increasing calcium excretion by kidneys.

What the evidence supports

Most data comes from preclinical animal studies. Human clinical trial evidence is limited or absent.

Graded Animal

Evidence drawn from in vivo animal models or in vitro systems. Mechanistically informative; translation to humans is unproven.

Key citations

Representative primary sources, including results that did not favour the compound.

  1. [1]

    Calcitonin in osteoporosis

    · DOI:10.1002/jbmr.1780 · 2013

  2. [2]

    Salmon calcitonin review

    · DOI:10.2165/00003495-200565150-00004 · 2005

  3. [3]

    Calcitonin in osteoporosis (2013)

    · · 0

  4. [4]

    Salmon calcitonin review (2005)

    · · 0

Citation records in this build are illustrative placeholders for the design.

Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.

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