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AnecdotalAntimicrobial peptide for respiratory defense

LL-37

Cathelicidin antimicrobial peptide for lung infection clearance.

Overview

Binds to formyl peptide receptors on immune cells and directly disrupts pathogen cell membranes.

Proposed mechanism

LL-37 is a cathelicidin-derived antimicrobial peptide that disrupts microbial membranes and modulates chemokine production in respiratory epithelium.

What the evidence supports

Evidence rests primarily on self-reported experience. Controlled studies are lacking.

Graded Anecdotal

Case reports, clinician notes, and user-reported outcomes. Recorded for completeness and labelled plainly so it is never mistaken for data.

Key citations

Representative primary sources, including results that did not favour the compound.

  1. [1]

    LL-37 in respiratory infection

    · DOI:10.1164/rccm.201708-1621OC · 2018

  2. [2]

    Cathelicidin in lung health

    · DOI:10.1038/nri2435 · 2008

  3. [3]

    LL-37 in respiratory infection (2018)

    · · 0

  4. [4]

    Cathelicidin in lung health (2008)

    · · 0

Citation records in this build are illustrative placeholders for the design.

Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.