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The library

149 compounds. Every one graded.

Filter by research area or by how strong the evidence actually is. Profiles graded Animal or Anecdotal are not hidden they are labelled, which is more useful.

Clinical
15
Human-limited
61
Animal
54
Anecdotal
19

16 of 149 profiles

Immune Support

ACTH 1-39

Clinical

Full-length adrenal hormone with broad receptor activity

ACTH 1-39 is the full-length, biologically active form of adrenocorticotropic hormone, a 39-amino acid peptide naturally secreted by the anterior pituitary gland. It primarily stimulates the adrenal cortex to produce cortisol, aldosterone, and adrenal androgens. Beyond adrenal signaling, ACTH 1-39 exerts direct effects on the brain, immune system, and peripheral tissues via melanocortin receptors.

0 RCT · 0 human · 0 preclinical

Immune

Erythropoietin (EPO)

Clinical

Oxygen-boosting hormone for endurance and anemia

Erythropoietin (EPO) is a glycoprotein hormone naturally produced primarily by the kidneys that regulates red blood cell production. Recombinant human EPO (rHuEPO) mimics this endogenous hormone to stimulate erythropoiesis in the bone marrow, increasing oxygen-carrying capacity. It is clinically approved for anemia associated with chronic kidney disease, chemotherapy, and certain other conditions, but is also widely misused as a performance-enhancing agent in endurance sports.

0 RCT · 0 human · 0 preclinical

Cardiovascular

Human Menopausal Gonadotropin (HMG)

Clinical

Dual gonadotropin for fertility and testicular function

Human Menopausal Gonadotropin (HMG) is a purified preparation of gonadotropins extracted from the urine of postmenopausal women, containing both Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) activity in approximately equal ratios. In clinical medicine it is used to stimulate ovulation in women and spermatogenesis in men, particularly those with hypogonadotropic hypogonadism. In performance and fertility contexts, HMG is used alongside or after hCG to restore or maintain testicular function, intratesticular testosterone production, and sperm output.

0 RCT · 0 human · 0 preclinical

sexual

Melanotan I

Clinical

Clinical-grade melanocyte activator for photoprotection

Melanotan I (afamelanotide) is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that potently stimulates melanogenesis, increasing skin pigmentation without requiring UV exposure. It was developed primarily to protect individuals with photosensitive conditions such as erythropoietic protoporphyria (EPP) from painful phototoxic reactions. Beyond tanning, it has demonstrated anti-inflammatory, photoprotective, and potentially immunomodulatory effects in clinical and preclinical studies.

0 RCT · 0 human · 0 preclinical

skin

ARA290 (Cibinetide)

Human-limited

Tissue-protective peptide for nerve repair and inflammation

ARA290, also known as Cibinetide, is a synthetic 11-amino acid peptide derived from the helix B surface peptide of erythropoietin (EPO) that selectively activates the innate repair receptor (IRR) without stimulating erythropoiesis. It is designed to harness the tissue-protective and anti-inflammatory properties of EPO while avoiding its hematopoietic side effects. Clinically, it has been investigated for neuropathic pain, small fiber neuropathy, and inflammatory conditions such as sarcoidosis.

0 RCT · 0 human · 0 preclinical

Immune

Glutathione

Human-limited

Master antioxidant for detox and cellular defense

Glutathione is a tripeptide antioxidant composed of glutamate, cysteine, and glycine that is naturally synthesized in virtually every cell of the body. It serves as the body's master antioxidant, neutralizing reactive oxygen species, supporting detoxification pathways, and maintaining redox homeostasis. Declining glutathione levels are associated with aging, chronic disease, and oxidative stress-related conditions.

0 RCT · 0 human · 0 preclinical

Immune

Lactoferrin

Human-limited

Iron-binding protein for immunity and gut barrier

Iron-binding glycoprotein for immune & gut health.

0 RCT · 0 human · 0 preclinical

Immune

LL-37

Human-limited

Human antimicrobial peptide for immunity and healing

LL-37 is a 37-amino acid human host defense peptide derived from the cathelicidin family, naturally produced by neutrophils, epithelial cells, and macrophages. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and viruses while simultaneously modulating immune responses and promoting wound healing. Research suggests it plays a critical role in innate immunity and may have therapeutic applications in chronic infections, wound repair, and inflammatory conditions.

0 RCT · 0 human · 0 preclinical

Immune

Thymalin/Thymulin

Human-limited

Thymic peptide restoring immune vitality with age

Thymalin is a thymic peptide preparation derived from calf thymus glands, while Thymulin (FTS) is a naturally occurring nonapeptide produced by thymic epithelial cells that requires zinc as a cofactor for biological activity. Together they represent thymic-origin immunomodulatory compounds that restore and regulate T-lymphocyte differentiation, maturation, and function. They are used primarily to support immune system integrity, combat immunosenescence, and may have applications in anti-aging and recovery protocols.

0 RCT · 0 human · 0 preclinical

Immune

Thymosin Alpha-1

Human-limited

Thymus peptide for immune system enhancement

Immune modulator for T-cell enhancement & infection support.

0 RCT · 0 human · 0 preclinical

Immune

Cortagen

Animal

Pineal-derived peptide for brain and immunity

Cortagen is a synthetic tetrapeptide (Ala-Glu-Asp-Pro) derived from the pineal gland and developed within the Russian peptide bioregulator program. It is primarily studied for its neuroprotective and immunomodulatory properties, with research suggesting it may support cortical function, slow age-related neurological decline, and modulate immune responses. Most of its evidence base comes from Russian preclinical and limited clinical studies conducted in the 1980s–2000s.

0 RCT · 0 human · 0 preclinical

cognition

FOXO4-DRI

Animal

Senolytic peptide targeting cellular senescence

FOXO4-DRI is a D-amino acid retro-inverso peptide designed to selectively induce apoptosis in senescent cells by disrupting the interaction between FOXO4 and p53. It belongs to a class of experimental senolytic compounds—agents that clear aged, dysfunctional 'zombie' cells from tissues. Research has been conducted primarily in mouse models, where it demonstrated improvements in fitness, fur density, kidney function, and lifespan metrics.

0 RCT · 0 human · 0 preclinical

longevity

PNC-27

Animal

Selective cancer cell membrane-targeting peptide

PNC-27 is a synthetic peptide derived from the p53 tumor suppressor protein, designed to selectively induce apoptosis in cancer cells while leaving normal cells unharmed. It contains an MDM-2-binding domain of p53 fused to a transmembrane-penetrating sequence, enabling it to insert into the membranes of cancer cells that aberrantly express HDM-2 on their surface. Research has been conducted primarily in vitro and in animal models, with very limited human data available.

0 RCT · 0 human · 0 preclinical

Immune

Thymulin

Animal

Thymus peptide for immune modulation

Thymus peptide for immune balance & T-cell maturation.

0 RCT · 0 human · 0 preclinical

Immune

Vilon

Animal

Thymus dipeptide for immune and DNA health

Thymus dipeptide for immune restoration & DNA repair.

0 RCT · 0 human · 0 preclinical

Immune

LL-37

Anecdotal

Cathelicidin peptide for innate immunity

Cathelicidin-derived antimicrobial & immune-modulating peptide.

0 RCT · 0 human · 0 preclinical

Immune

Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.