The library
149 compounds. Every one graded.
Filter by research area or by how strong the evidence actually is. Profiles graded Animal or Anecdotal are not hidden they are labelled, which is more useful.
- Clinical
- 15
- Human-limited
- 61
- Animal
- 54
- Anecdotal
- 19
11 of 149 profiles
Sexual Health
Gonadorelin Acetate
ClinicalPreserve natural testosterone via HPG axis activation
Gonadorelin Acetate is a synthetic decapeptide identical to endogenous gonadotropin-releasing hormone (GnRH), produced and secreted by the hypothalamus. It stimulates the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), thereby supporting endogenous testosterone and estrogen production. It is used clinically to assess pituitary function, treat hypogonadism, support fertility, and is increasingly used alongside anabolic protocols to preserve testicular function.
0 RCT · 0 human · 0 preclinical
sexual
Human Chorionic Gonadotropin (HCG)
ClinicalThe LH Mimic for Hormonal Restoration
Human Chorionic Gonadotropin (HCG) is a glycoprotein hormone naturally produced by the placenta during pregnancy, structurally similar to luteinizing hormone (LH). In clinical and research settings, it is used to stimulate testosterone production in men, support fertility, and maintain testicular function during or after anabolic steroid use. It acts directly on the gonads to mimic LH signaling, making it a cornerstone of hormonal restoration protocols.
0 RCT · 0 human · 0 preclinical
sexual
Human Menopausal Gonadotropin (HMG)
ClinicalDual gonadotropin for fertility and testicular function
Human Menopausal Gonadotropin (HMG) is a purified preparation of gonadotropins extracted from the urine of postmenopausal women, containing both Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH) activity in approximately equal ratios. In clinical medicine it is used to stimulate ovulation in women and spermatogenesis in men, particularly those with hypogonadotropic hypogonadism. In performance and fertility contexts, HMG is used alongside or after hCG to restore or maintain testicular function, intratesticular testosterone production, and sperm output.
0 RCT · 0 human · 0 preclinical
sexual
Oxytocin Acetate
ClinicalThe bonding hormone for trust and connection
Oxytocin Acetate is the acetate salt form of oxytocin, a naturally occurring nonapeptide hormone synthesized in the hypothalamus and released by the posterior pituitary gland. It plays central roles in social bonding, trust, stress reduction, sexual function, and uterine contraction. Research has expanded its potential applications to include anxiety reduction, prosocial behavior enhancement, and modulation of the hypothalamic-pituitary-adrenal (HPA) axis.
0 RCT · 0 human · 0 preclinical
mood
PT-141
ClinicalCentral nervous system sexual desire activator
PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist originally derived from the tanning peptide Melanotan II. It is used to treat hypoactive sexual desire disorder (HSDD) and erectile dysfunction by acting centrally on the brain rather than peripherally on blood vessels. Unlike PDE5 inhibitors, PT-141 works through the central nervous system to increase sexual desire and arousal in both men and women.
0 RCT · 0 human · 0 preclinical
sexual
Triptorelin Acetate
ClinicalGnRH analogue for hormonal axis modulation
Triptorelin Acetate is a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) used clinically to treat hormone-sensitive conditions such as prostate cancer, endometriosis, and central precocious puberty. Upon initial administration it causes a transient surge in luteinizing hormone (LH) and follicle-stimulating hormone (FSH), followed by sustained suppression of gonadal steroid production through pituitary receptor desensitization. In research and off-label contexts, single low-dose administration has been explored as a means to transiently restore hypothalamic-pituitary-gonadal (HPG) axis function in individuals with post-anabolic-steroid-induced hypogonadism.
0 RCT · 0 human · 0 preclinical
sexual
Gonadorelin
Human-limitedGonadotropin-releasing hormone agonist
GnRH analog for fertility and hormonal assessment.
0 RCT · 0 human · 0 preclinical
sexual
Kisspeptin-10
Human-limitedEndogenous HPG axis activator for sexual health
Kisspeptin-10 is the biologically active C-terminal decapeptide fragment of the larger kisspeptin precursor protein, encoded by the KISS1 gene. It acts as a potent endogenous activator of the hypothalamic-pituitary-gonadal (HPG) axis, stimulating the release of gonadotropin-releasing hormone (GnRH) and downstream luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It is investigated for applications in reproductive endocrinology, sexual function, and mood regulation.
0 RCT · 0 human · 0 preclinical
sexual
Leuprolide (Lupron)
Human-limitedLong-acting GnRH agonist for hormone therapy
Long-acting GnRH agonist for hormone suppression.
0 RCT · 0 human · 0 preclinical
sexual
Melanotan II
Human-limitedPotent tanning and libido melanocortin agonist
Melanotan II (MT-II) is a synthetic cyclic heptapeptide analogue of alpha-melanocyte-stimulating hormone (α-MSH) originally developed at the University of Arizona. It potently activates melanocortin receptors to stimulate skin tanning, increase sexual arousal, and suppress appetite. Unlike natural α-MSH, its cyclic structure confers greater receptor affinity and metabolic stability.
0 RCT · 0 human · 0 preclinical
skin
PT-141 (Bremelanotide)
Human-limitedMelanocortin receptor agonist for sexual function
Melanocortin agonist for sexual health & libido.
0 RCT · 0 human · 0 preclinical
sexual
Reference information for research purposes. Not medical advice, and not a recommendation to use any compound. Many entries describe substances that are not approved for human use.